Recombinant plasmid containing human interferon-beta gene

Details Recombinant plasmid containing human interferon-beta gene Recombinant plasmid containing human interferon-beta gene

1982-12-22

1987-08-11

Martinell, Ph.D., James

Chemistry: molecular biology and microbiology

Vector, per se

435 60, 435 69, 435 70, 435 71, 435 91, 4351723, 435253, 536 27, C12N 100, C12N 1500, C12N 120, C12P 2100, C12P 2106, C12P 2102, C12P 2104, C12P 1934, C07H 2104

Patent

active

046861912

ABSTRACT:
Recombinant vector plasmids containing a DNA fragment coding for human interferon-.beta. inserted downstream from a tryptophan promoter are useful for transformation of microorganisms such as Escherichia coli which transformants produce human interferon-.beta..

REFERENCES:
patent: 4349629 (1982-09-01), Carey et al.
Taniguchi et al.: Gene 10, 11 (1980).
Taniguchi et al.: Proc. Natl. Acad. Sci., USA 77, 5230 (1980).
Tacon et al.: Molec. gen. Genet. 177, 427 (1980).
Emtage et al.: Nature 283, 171 (1980).
Hallewell et al.: Gene 9, 27 (1980).
Goeddel et al.: Nature 281, 544 (1979).
Edman et al.: Nature 291, 503 (1981).
Young et al.: Cell 17, 225 (1979).
M. Houghton, et al., Proc. Battelle Conf. Genet. Eng. 1981 5, 51-57 (Eng.).
M. Houghton, Chemical Abstracts, vol. 97, No. 7, (1982), p. 168, No. 50595W, "The Cloning and Expression of a Human Fibroblast Interferon Gene in Bacteria".
H. Shepard et al., Chemical Abstracts, vol. 96, No. 21 (1982), p. 174, No. 175316s, "Increased Synthesis in E. Coli of Fibroblast and Leukocyte Interferons through Alterations in Ribosome Bindiny Sites".
J. D. Windass, et al., Nucleic Acids Research, vol. 10, No. 21, (1982), pp. 6639-6657, "The Construction of a Synthetic Escherichia Coli Trp promoter and its use in the Expression of a Synthetic Interferon Gene".
D. V. Goeddell, et al., Nucleic Acids Research, vol. 8, No. 18, (1980), pp. 4057-4074, "Synthesis of Human Fibroblast Interferon by E. Coli".
G. F. Miozzari, et al., J. Bact., vol. 133, No. 3, (1978), pp. 1457-1466, "Translation of the Leader region of the Escherichia Coli Tryptophan Operon".
G. N. Bennett, et al., Mol. Biol., vol. 121, (1978), pp. 113-137, "Nucleotide Sequence of the promoter-Operator Region of the Tryptophan Operon of Escherichia Coli".
F. Lee, et al., J. Mol. Biol., vol. 121, (1978), pp. 193-217, "Comparison of the Nucleotide Sequences of the Initial Transcribed Regions of the Tryptophan Operons of Escherichia Coli and Salmonella Typhimurium".

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