Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2002-09-05
2008-11-18
Chang, Celia (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S242000, C514S252050, C514S255050, C514S256000, C514S336000, C514S342000, C514S343000, C544S238000, C544S328000, C544S405000, C546S193000, C546S268400, C546S272700
Reexamination Certificate
active
07452906
ABSTRACT:
Compounds and their use as pharmaceuticals particularly as Raf kinase inhibitors for the treatment of neurotraumatic diseases, cancer, chronic neurodegeneration, pain, migraine and cardiac hypertrophy.
REFERENCES:
patent: 2 306 108 (1997-04-01), None
patent: WO 95/03297 (1995-02-01), None
patent: WO 02/24680 (2002-03-01), None
Dluzniewska et al. “Transient cerebral ishemiia . . . ” SciSearch 13712750 (2005).
Wermuth “The practice of medicinal chemistry” Acd. Press p. 203-213 (1996).
Grever et al. “The national cancer institute . . . ” Seminars in oncology v. 19, p. 622-638 (1992).
Lange et al. “Bioisosteric replacement . . . ” J. Med. Chem. v48, 1823-1838 (2005).
IlaSircar et al. “Nonpeptide angiotensin II . . . ” J. Med. Chem. v. 36, p. 2253-65 (1993).
Keller et al. “The role of Raf kinase . . . ” Biochem. Pharm. v.68, pp. 1049-1053 (2004).
Merck Index p. 4149, 4811 (1979).
Kelley et al. “Synthesis and . . . ” J. Med. chem. v.38, p. 3884-3888(1995).
Bamford Mark James
Dean David Kenneth
Naylor Antoinette
Takle Andrew Kenneth
Wilson David Matthew
Chang Celia
Hsu Grace C.
Kinzig Charles M.
McCarthy Mary E.
SmithKline Beecham P.L.C.
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