Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing
Reexamination Certificate
2004-02-26
2008-11-25
Kumar, Shailendra (Department: 1621)
Organic compounds -- part of the class 532-570 series
Organic compounds
Amino nitrogen containing
C564S036000, C564S149000, C548S304400, C548S333500, C548S361100, C548S371100, C548S469000, C544S224000, C544S242000, C544S336000, C546S291000, C546S292000
Reexamination Certificate
active
07456315
ABSTRACT:
The present invention relates to non-steroidal ligands for use in nuclear receptor-based inducible gene expression system, and a method to modulate exogenous gene expression in which an ecdysone receptor complex comprising: a DNA binding domain; a ligand binding domain; a transactivation domain; and a ligand is contacted with a DNA construct comprising: the exogenous gene and a response element; wherein the exogenous gene is under the control of the response element and binding of the DNA binding domain to the response element in the presence of the ligand results in activation or suppression of the gene.
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Carlson Glenn Richard
Chortyk Orestes
Hormann Robert Eugene
Meyer Andrew
Opie Thomas R.
Intrexon Corporation
Kumar Shailendra
Sterne Kessler Goldstein & Fox P.L.L.C.
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