Methods for assaying expression of novel galanin receptors

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

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C435S007100, C435S007200, C435S007210, C436S501000

Reexamination Certificate

active

07407761

ABSTRACT:
The present invention is directed to methods for assaying a test compound's ability to alter the expression of novel receptor for galanin which has been designated as galanin receptor 2. The invention also encompasses both the receptor protein as well as nucleic acids encoding the protein. In addition, the present invention is directed to additional methods and compositions which rely upon either GAL-R2 proteins or nucleic acids.

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Howard et al. Molecular cloning and characterization of a new receptor for galanin. (1997) FEBS Letters 405:285-290.
Abstract for French counterpart of WO 95/22608, listed in the Foreign Patent Documents as document 2, 1995.
Burgevin et al., “Cloning, pharmacological characterization, and anatomical distribution of a rat cDNA encoding for a galanin receptor,” Journal of Molecular Neuroscience (1995) 6:33-41.
Habert-Ortoli et al., “Molecular cloning of a functional human galanin receptor,” PNAS (1994) 91(21):9780-9783.

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