Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2004-02-03
2008-10-28
Saeed, Kamal (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S398000, C548S302700, C548S331500
Reexamination Certificate
active
07442717
ABSTRACT:
Novel substituted 2-aminoimidazoles of formula I, process for their preparation, their use as medicament or diagnostic aid, and medicament containing them. The compounds of this type are useful in the prevention or treatment of various disorders and can be employed inter alia for renal disorders such as acute or chronic renal failure, for disorders of biliary function, for respiratory disorders such as snoring or sleep apneas or for stroke
REFERENCES:
patent: 3459763 (1969-08-01), Gruenfeld
patent: 4275072 (1981-06-01), Karjalainen et al.
patent: 6005010 (1999-12-01), Schwark
patent: 0254259 (1988-01-01), None
patent: 1131191 (1968-10-01), None
patent: WO90/14338 (1990-11-01), None
patent: WO95/19968 (1995-07-01), None
patent: WO01/21160 (2001-03-01), None
patent: WO01/21582 (2001-03-01), None
patent: WO01/72742 (2001-10-01), None
patent: WO01/79186 (2001-10-01), None
patent: WO02/20496 (2002-03-01), None
U.S. Appl. No. 09/975,566, filed Oct. 11, 2001, Collins et al.
U.S. Appl. No. 10/448,851, filed May 30, 2003, Lang.
U.S. Appl. No. 10/000,028, filed Dec. 4, 2001, Hofmeister.
U.S. Appl. No. 10/323,799, filed Dec. 20, 2002, Heinelt.
U.S. Appl. No. 09/734,008, filed Dec. 12, 2000, Heinelt.
Akhter, et al., Squalamine, a Novel Cationic Steroid, Specifically Inhibits the Brush-border Na+/H+ Exchanger Isoform NHE3, The American Physiological Society, 1999, pp. c136-c144.
Ernsberger, et al., Clonidine Binds To Imidazole Binding Sites As Well As Alpha2-Adrenoceptors In The Ventrolateral Medulla, European Journal of Pharmacology, 134 (1987) pp. 1-13.
Fliegel, et al., Regulation And Characterization Of The Na+/H+ Exchanger, Biochem. Cell. Biol., 76: (1998), pp. 735-741.
Jen, et al., Amidines and Related Compounds. 6. Studies on Structure-Activity Relationships of Antihypertensive and Antisecretory Agents Related to Clonidine, Journal of Medicinal Chemistry, 1975, vol. 18, No. 1., pp. 90-99.
Ma, et al., Expression And Localization Of Na+/H+ Exchangers In Rat Central Nervous System, Neuroscience. (1997), vol. 79. No. 2. pp. 591-603.
Orlowski, et al., Molecular Cloning Of Putative Members Of The Na/H Exchanger, J. Biological Chemistry, 1992, vol. 267, pp. 9331-9339.
Heinelt Uwe
Hofmeister Armin
Jansen Hans-Willi
Lang Hans-Jochen
Wirth Klaus
Bell Craig M.
Coppins Janet L
Saeed Kamal
Sanofi-Aventis Deutschland GmbH
LandOfFree
Substituted 2-aminoimidazoles, process for their... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Substituted 2-aminoimidazoles, process for their..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted 2-aminoimidazoles, process for their... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4012581