Compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S393000, C514S394000, C546S118000, C548S304400

Reexamination Certificate

active

07407968

ABSTRACT:
Compounds of formula (I) wherein RF1, RF2, Z, R1, R2, Ar, X and Y are as defined in the specification as well as salts and pharmaceutical compositions including the compounds were prepared. These compounds are useful in therapy, in particular in the management of pain.

REFERENCES:
patent: 2945044 (1960-07-01), Hoffmann et al.
patent: 7030139 (2006-04-01), Cheng et al.
patent: 2006/0135554 (2006-06-01), Cheng et al.
patent: 0445781 (1991-09-01), None
patent: 1481049 (1967-05-01), None
patent: WO 97/19063 (1997-05-01), None
patent: WO 00/46209 (2000-08-01), None
patent: WO 02/36590 (2002-05-01), None
patent: WO 02/060447 (2002-08-01), None
patent: 02/085866 (2002-10-01), None
patent: WO 02/085866 (2002-10-01), None
patent: 03/053938 (2003-07-01), None
patent: WO 2004/035548 (2004-04-01), None
Mcpartland et al., The Journal of Comparative neurology, vol. 436, pp. 423-429.
STN International, file CAPLUS, CAPLUS accession No. 1973:87, document No. 78:87, Paglietti G. et al, “Dialkylaminoalklybenzimidazoles of pharmacological interest”, & Studi Sassaresi, Sezione 2: Archivio Bimestrale di Scienze Mediche e Naturali (1971), 49(5-6), 192-203.
Seki, T, et al., “2-Benzimidazolethiol derivatives . . . -5-substituted, benzimidazole”, Chem. Abstracts, 1969, p. 445, vol. 71, No. 13, The Abstract, No. 61291h, Yakugaku Zasshi, 1969, 89 (5), 617-626.
Paglietti, G. et al., “Dialkylaminoalkylbenzimidazoles of pharmacological interest III”, Chem. Abstracts, 1972, p. 479, vol. 77, No. 7, The Abstract, No. 48338h, Farmaco, Ed. Sci. 1972, 27 (4), 333-342.
Lecolier, S. et al., “New benzimidazoles with morphine activity”, Chim. Ther., 1967, pp. 16-24, vol. 2, No. 1.
Burke, T. et al., “Probes for Narcotic Receptor Mediated Phenomena. 7.1Synthesis and Pharmacological Properties of Irreversible Ligands Specific for μ or δ Opiate Receptors”, J. Med. Chem., 1984, pp. 1570-1574, vol. 27.
Smith, J. et al., “Necklace-Coded Polymer-Supported Combinatorial Synthesis of 2-Arylaminobenzimidazoles”, J. Comb. Chem., 1999, pp. 368-370, vol. 1.
Monhemius et al., “CB1 Receptor Mediated Analgesia from the Nucleus Reticularis Gigantocellularis Pars Alpha is Activated in an Animal Model of Neuropathic Pain,” Brain Research, 2001, vol. 908, pp. 67-74.

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