Process for the preparation of Tazobactam in pure form

Details Process for the preparation of Tazobactam in pure form Process for the preparation of Tazobactam in pure form

2005-04-05

2008-08-26

Berch, Mark L (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

07417143

ABSTRACT:
An improved process for the purification of tazobactam or its derivatives of the formula (I)wherein R represents hydrogen, C1-C6alkyl, p-methoxybenzyl, o-nitrobenzyl, p-nitrobenzyl, o-chlorobenzyl, benzyl or diphenylmethyl, which comprises the steps of:i) slurrying the compound of formula (I) containing the impurity of the formula (V) using a solvent in the presence or absence of tartaric acid with or without the presence of water at 20-50° C. andii) isolating the compound of formula (I) in pure form.

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patent: 2004/0162277 (2004-08-01), Shimbayashi et al.
patent: A-63-066187 (1988-03-01), None

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