Ethynyl derivatives as factor Xa inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S346000, C514S388000, C544S122000, C544S131000, C544S157000, C544S165000, C546S291000, C548S331500

Reexamination Certificate

active

07427618

ABSTRACT:
Novel compounds of the formula (I), in which R1, R2, R3, X and Y have the meaning indicated in Patent claim1,are inhibitors of coagulation factor Xa and can be employed for the prophylaxis and/or therapy of thromboembolic diseases and for the treatment of tumors.

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patent: 2004/0038858 (2004-02-01), Dorsch et al.
patent: 10102322 (2002-07-01), None
patent: WO 02-48099 (2002-06-01), None
patent: WO 02-079145 (2002-10-01), None
Gould et al., Current Pharmaceutical Design, 9, 2337-2347, 2003.
Kaiser et al., Thrombosis Research, 98, 175-185, 2000.
Morales-Asin, F., Headache, 40, 45-47, 2000.
Wang et al., Stroke, 34, 468-474, 2003.

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