Microscope system and methods for intracellular studies

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

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C435S455000, C435S468000, C435S471000

Reexamination Certificate

active

07368240

ABSTRACT:
A microscope system, kit and method are described for observation of cellular activity in real time. The system is used to monitor cell transfection using a polynucleotide noncovalently attached to a carrier, The carrier labeled with a dye or fluorescent agent so that transport of complex can be monitored in real time. The polynucleotide includes both a gene of interest and a reporter gene. The reporter gene indicates successful expression of the gene of interest.

REFERENCES:
patent: 5902246 (1999-05-01), McHenry et al.
patent: 5919445 (1999-07-01), Chao
patent: 2005/0265978 (2005-12-01), Chancellor et al.

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