Vaccine to control equine protozoal myeloencephalitis in horses

Details Vaccine to control equine protozoal myeloencephalitis in horses Vaccine to control equine protozoal myeloencephalitis in horses

2000-02-24

2008-09-02

Bertoglio, Valarie (Department: 1632)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

C424S269100

Reexamination Certificate

active

07419668

ABSTRACT:
The present invention provides vaccines and methods for making the vaccines that actively or passively protect an equid or other animal againstSarcocystis neurona. In particular, the present invention provides vaccines that provide active immunity which comprise a polypeptide or DNA vaccine that contains or expresses at least one epitope of an antigen that has an amino acid sequence substantially similar to a unique 16 (±4) kDa antigen and/or 30 (±4) kDa antigen ofSarcocystis neurona. The present invention further provides a vaccine that provides passive immunity toSarcocystis neuronacomprising polyclonal or monoclonal antibodies against at least one epitope of an antigen substantially similar to a unique 16 (±4) kDa antigen and/or 30 (±4) kDa antigen ofSarcocystis neurona.

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