Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-05-20
1994-07-12
Ivy, C. Warren
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514317, 514319, 514321, 546196, 546197, 546198, 546205, 546206, 546239, 546234, 546236, C07D21126, A61K 31445
Patent
active
053289170
ABSTRACT:
The present invention relates to piperidine derivatives of the formula: ##STR1## wherein, R, R.sup.1, R.sup.3, X, and n are defined in the specification, pharmaceutical compositions thereof and methods of treating anoxia, traumatic injury, ischemia, migraine and epilepsy.
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patent: 4877799 (1989-10-01), Drejer
patent: 5017585 (1991-05-01), Jakobsen
patent: 5019582 (1991-05-01), Drejer
Greenberg "Current Neurology" by Appel, pp. 93-109 (1987).
Scarpelli "Cell Injury" pp. 44-45 Apr., 1986.
Nachshen "The Effect of Some Organic Calcium Antagonist on Cainylux in Presynoptic Nerve Terminals" Mol. Pharm. 16 579-586 (1979).
Jakobsen Palle
Kanstrup Anders
Lundbeck Jane M.
Chang Celia
Ivy C. Warren
Lambiris Elias J.
Novo Nordisk A S
Zelson Steve T.
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