Cross-linked glycopeptide—cephalosporin antibiotics

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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C514S002600, C514S201000, C514S202000, C514S206000

Reexamination Certificate

active

07341993

ABSTRACT:
This invention provides cross-linked glycopeptide-cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.

REFERENCES:
patent: 4220761 (1980-09-01), Takaya et al.
patent: 4341775 (1982-07-01), Takaya et al.
patent: 4366153 (1982-12-01), Takaya et al.
patent: 4427677 (1984-01-01), Takaya et al.
patent: 4487767 (1984-12-01), Takaya et al.
patent: 4550102 (1985-10-01), Teraji et al.
patent: 4603129 (1986-07-01), Blumbach et al.
patent: 4647556 (1987-03-01), Lattrell et al.
patent: 4667028 (1987-05-01), Schwab et al.
patent: 4668783 (1987-05-01), Ochiai et al.
patent: 4840945 (1989-06-01), Ohnishi et al.
patent: 4921851 (1990-05-01), Kishimoto et al.
patent: 4943567 (1990-07-01), Nishizawa et al.
patent: 5071979 (1991-12-01), Lattrell et al.
patent: 5693791 (1997-12-01), Truett et al.
patent: 6437119 (2002-08-01), Truett
patent: 6878686 (2005-04-01), Marquess et al.
patent: 6974797 (2005-12-01), Fatheree et al.
patent: 6995138 (2006-02-01), Marquess et al.
patent: 2004/0033939 (2004-02-01), Marquess et al
patent: 2004/0266666 (2004-12-01), Fatheree et al.
patent: 2005/0026818 (2005-02-01), Fatheree et al.
patent: 2 033 377 (1980-05-01), None
patent: 60-41682 (1985-03-01), None
patent: WO 97/41128 (1997-11-01), None
patent: WO 99/42476 (1999-08-01), None
patent: WO 99/64049 (1999-12-01), None
patent: WO 00/39156 (2000-07-01), None
http://cancerweb.ncl.ac.uk/cgi-bin/omd?query=phenylene.
http://en.wikipedia.org/wiki/Substitution—reaction.
http://en.wikipedia.org/wiki/Functional—group.
U.S. Appl. No. 09/457,926, filed Dec. 8, 1999, Christensen et al.
Boeckh, M. et al., “Pharmacokinetics and Serum Bactericidal Activity of Vancomycin Alone and in Combination with Ceftazidime in Healthy Volunteers.” Antibacterial Agents and Chemotherapy, vol. 32. No. 1, pp. 92-95 (1988).
Hammes, W. P., “Biosynthesis of peptidoglycan inGaffkya homari. The mode of action of penicillin G and mecillinam”, Chemical Abstracts, vol. 86, No. 5, Abstract No. 26406 (Jan. 31, 1977).
Kim, M. et al., “Synthesis and Antibacterial Activity of Cephalosporins Having Hydroxamic Acid at C-7 Position.” Biorganic & Med. Chem. Letters, vol. 6, No. 17, pp. 2077-2080 (1996).
Lattrell, R. et al., “Synthesis and Structure-Activity Relationships in the Cefpirome Series.” Journal of Antibiotics, vol. XLI, No. 10, pp. 1374-1394.
Rao, J. et al., “Tight Binding of a Dimeric Derivative of Vancomycin with Dimeric L-Lys-D-Ala-D-Ala.” J. Am. Chem. Soc., vol. 119, pp. 10286-10290 (1997).
Renoud-Grappin, M. et al., “Imidazo[1,5-b]pyridazine-d4T conjugates:synthesis and anti-human Immunodeficiency virus evaluation.” Antiviral Chemistry & Chemotherapy, vol. 9, pp. 205-223.
Staroske, T. et al., “Synthesis of Covalent Head-to-Tail Dimers of Vancomycin.” Tetrahedron Letters 39, pp. 4917-4920 (1998).
Sundram, U. et al., “General and Efficient Method for the Solution- and Solid-Phase Synthesis of Vancomycin Carboxamide Derivatives.” J. Org. Chem., vol. 60, pp. 1102-1103 (1995).
Sundram, U. et al., “Novel Vancomycin Dimers with Activity against VAncomycin-Resistant Enterococci” J. Am. Chem. Soc. , vol. 118, pp. 13107-13108 (1996).

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