Compounds, vectors and methods for expressing human, cytosolic p

Details Compounds, vectors and methods for expressing human, cytosolic p Compounds, vectors and methods for expressing human, cytosolic p

1993-04-12

1994-07-12

Wax, Robert A.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

435 691, 435 703, 435 712, 435198, 4351723, 4352523, 43525233, 4353201, 536 232, 935 14, 935 29, 935 32, 935 56, 935 70, 935 71, 935 73, C12N 1555, C12N 1570, C12N 1585

Patent

active

053288424

ABSTRACT:
The invention includes recombinant DNA compounds, vectors and methods useful for expressing an exceptionally rare, human, cytosolic phospholipase A.sub.2 (cPLA.sub.2) enzyme. The invention also includes a method for screening compounds to identify inhibitors of cPLA.sub.2 which is believed to partake in several disease processes.

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Belyavsky et al., "PCR-based cDNA Library construction . . . " Nuc. Acids. Res. 17:2919-2932 (Apr. 1989).
Berger et al. (eds) "Guide to Molecular Cloning Techniques" Methods in Enzymology 152:432-447, 661-704 (1987).
Deutscher (ed.) "Guide to Protein Purification" Methods in Enzymology 182:602-613, 738-751 (1990).
Shapiro (ed.) "Mobile Genetic Elements" Chapter 4 pp. 159-221.

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