Compounds and compositions as protein kinase inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C540S522000

Reexamination Certificate

active

10836030

ABSTRACT:
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases and disorders associated with kinase activity, particularly diseases associated with the activity of CDK1, CDK2, CDK4, CDK5, GSK3β, Bcr-ab1, Flt-3, c-Kit, PDGFRβ, Src, Mek1 and CK1.

REFERENCES:
patent: 5621099 (1997-04-01), Annoura et al.
patent: 6197954 (2001-03-01), Horne et al.
patent: 2003/0105075 (2003-06-01), Meijer
patent: 2004/0235820 (2004-11-01), Tepe
patent: WO 01/05794 (2001-01-01), None
patent: WO 01/64680 (2001-09-01), None
Sosa, Ana, et al. A Practical Systhesis of (Z)-Debromohymenialdisine, J. Org. Chem. 2000, vol. 65, pp. 610-611.
Xu, Ying-zi, et al. Synthesis of C11N5 Marine Sponge Alkaloids: -Hymenin, Stevensine, Hymenialdisine, and Debromohymenialdisine, J. Org. Chem., 1997, vol. 62, pp. 456-464.
Chacun-Lefevre, Lidwine. Intramolecular Heck Coupling of Alkenyl 3-Iodoindole-2-carboxamide Derivatives, Synlett 2001, No. 6, pp. 848-850.
Annoura, H., et al. Total Syntheses of Hymenialdisine and Debromohymenialdisine: Stereospecific Construction of the 2-Amino-4-Oxo-2-Imidazolin-5(Z)-Disubstituted Ylidene Ring System, Tetrahedron Letters, 1995, vol. 36, No. 3, pp. 413-416.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Compounds and compositions as protein kinase inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compounds and compositions as protein kinase inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compounds and compositions as protein kinase inhibitors will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3954368

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.