(Halo-benzo carbonyl)heterobi cyclic p38 linase inhibiting...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Details

C514S264100, C514S252140, C544S279000, C544S117000, C546S303000, C546S334000

Reexamination Certificate

active

10517754

ABSTRACT:
Compounds described by the chemical formula (I) or pharmaceutically acceptable salts thereof: (I) are inhibitors of p38 and are useful in the treatment of inflammation such as in the treatment of rheumatoid arthritis, rheumatoid spondylitis, osteoarthritis, gouty arthritis and other arthritic conditions; inflamed joints, eczema, psoriasis or other inflammatory skin conditions such as sunburn; inflammatory eye conditions including conjunctivitis; pyresis, pain and other conditions associated with inflammation

REFERENCES:
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Hashimoto, et al.,J Pharmacol. and Experim. Therap., vol. 293, No. 2, pp. 370-375, 2000.
Johnson, et al., Science, vol. 298 Dec. 6, 2002, 1911-1912.
Schreiber, et al., Clin, Gastroenterol. Hepatol., 2006, Mar; 4(3):325-34 (PubMed abstract).
Viral Defense Foundation, <http://www.viraldefense.org/mission.htm>, downloaded May 16, 2007.
Visiting Nurse Assns. of America, <http://www.vnaa.org/vnaa/gen/Germ—Protection—Center—Cold—and—Flu—Resources,html...>, downloaded May 16, 2007.
Boehm, Expert Opinion Therapeutic Patents (2000) 10(1), p 25.
Dodeller, Arthritis Research & Therapy 2006, 8:205.
Viral Defence Foundation, <http://www.viraldefence.org/mission.htm>, downloaded May 16, 2007.
Visiting Nurse Assns. of America, <http://www.vnaa.org/vnaa/gen/Germ—Protection—Center—Cold—and—Flu—Resources, html...>, downloaded May 16, 2007.

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