Method of making 7-(4-bromobutoxy)-3,4-dihydrocarbostyril

Details Method of making 7-(4-bromobutoxy)-3,4-dihydrocarbostyril Method of making 7-(4-bromobutoxy)-3,4-dihydrocarbostyril

2008-04-22

2008-04-22

Seaman, D. Margaret (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

C546S158000

Reexamination Certificate

active

11053072

ABSTRACT:
The invention encompasses synthesizing 7-(4-bromobutoxy)-3,4-dihydrocarbostyril by mixing 7-hydroxy-tetrahydroquinolinone, dibromobutane, and at least one base to form a reaction mixture; heating the reaction mixture; cooling the reaction mixture; and isolating the 7-(4-bromobutoxy)-3,4-dihydrocarbostyril from the reaction mixture. The invention also encompasses using phase transfer catalysts during the reaction.

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