Methods and apparatus for testing disruption of a vagal nerve

Surgery: light – thermal – and electrical application – Light – thermal – and electrical application – Electrical therapeutic systems

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

Reexamination Certificate

active

11067185

ABSTRACT:
Method and apparatus for disrupting a gastric vagal nerve in the gastroesophageal region and testing the function and disruption of the vagal nerve. In one example embodiment, a treatment device applies ultrasound at a high energy level, such as high intensity focused ultrasound, to a vagal nerve to disrupt it and then ultrasound at a lower energy level to another portion of the vagal nerve, preferably further from the stomach, so as to stimulate the vagal nerve. Alternative ways to test the function or disruption of the vagal nerve involve using PCP-GABA, a pancreatic polypeptide, pressure changes inside the stomach, the gastric mucusol pH, a dye agent in the stomach, and other tests.

REFERENCES:
patent: 3128760 (1964-04-01), Baker
patent: 5188104 (1993-02-01), Wernicke et al.
patent: 5263480 (1993-11-01), Wernicke et al.
patent: 5471988 (1995-12-01), Fujio et al.
patent: 5807285 (1998-09-01), Vaitekunas et al.
patent: 5878749 (1999-03-01), Miller
patent: 6197022 (2001-03-01), Baker
patent: 6405732 (2002-06-01), Edwards et al.
patent: 6427089 (2002-07-01), Knowlton
patent: 6591137 (2003-07-01), Fischell et al.
patent: 6609025 (2003-08-01), Barrett et al.
patent: 6826428 (2004-11-01), Chen et al.
patent: 7160258 (2007-01-01), Imran et al.
patent: 2002/0032468 (2002-03-01), Hill et al.
patent: 2002/0087192 (2002-07-01), Barrett et al.
patent: 2002/0103424 (2002-08-01), Swoyer et al.
patent: 2002/0198470 (2002-12-01), Imran et al.
patent: 2003/0023287 (2003-01-01), Edwards et al.
patent: 2003/0028111 (2003-02-01), Vaezy et al.
patent: 2003/0144708 (2003-07-01), Starkebaum
patent: 2004/0082859 (2004-04-01), Schaer
patent: 2004/0181178 (2004-09-01), Aldrich et al.
patent: 2004/0186468 (2004-09-01), Edwards
patent: 2005/0021101 (2005-01-01), Chen et al.
patent: WO 00/69376 (2000-11-01), None
patent: WO 01/00273 (2001-01-01), None
patent: WO 01/22897 (2001-04-01), None
Bell, P.R.F., The Long Term Effect Of Vagotomy On the Maximal Acid Response To Histamine In Man, Univ. Dept. of Surgery, Royal Infirmary, Sheffield, England, vol. 46, No. 4, pp. 387-391, 1963.
Burge, H. et al., Method Of Testing For Complete Nerve Section During Vagotomy, British Medical Journal, Mar. 15, 1958, pp. 615-618.
Burge, H. et al., The Technique Of Bilateral Selective Vagotomy With The Electrical Stimulation Test, Brit. J. Surg., vol. 56, No. 6, Jun. 1969, pp. 452-460.
Date, Y. et al., The Role of the Gastric Afferent Vagal Nerve in Ghrelin-Induced Feeding and Growth Hormone Secretion in Rats, Gastroenterology 2002; 123: 1120-1128.
Date, Y. et al., Ghrelin Acts in the Central Nervous System to Stimulate Gastric Acid Secretion, Biochem. and Biophys. Res. Communications, 280, 904-907 (2001).
Goto, Y. et al., A New Intraoperative Test for Completeness of Vagotomy: The PCP-GABA (Beta-Parachiorophenol-Gamma-Aminobutyric Acid) Test, The American J. of Surgery, vol. 147, Jan. 1984, pp. 159-163.
Grassi, G. et al., Intraoperative Relation Of Gastic Secretion Acidity And Complete Vagotomy, Surgery, Gynecology & Obstetrics, vol. 134, Jan. 1972, pp. 35-38.
Hennessy, T.P.J. et al., An improved preoperative test of vagal section, Annals of the Royal College of Surgeons of England, vol. 61, 1979, pp. 474-476.
Kral, J.G. et al., Gastroplasty for Obesity: Long-Term Weight Loss Improved by Vagotomy, World J. Surg. 17, 75-79 (1993).
Kral, J. G., Surgical Treatment of Obesity, Medical Clinics of North America, vol. 73, No. 1, Jan. 1989.
Kral, J.G., Behavioral effects of vagotomy in humans, J. of Autonomic Nervous System, 9 (1983) 273-281.
Kral, J.G. et al. Truncal vagotomy in morbid obesity, Int'l J. Obesity (1981) 5, 431-435.
Nagammapudur, S. et al., A Safe and Noninvasive Test for Vagal Integrity Revisited, Arch. Surg., vol. 137, Aug. 2002, pp. 954-957.
Ross, B. et al., The Insulin Test After Vagotomy, The Univ. Dept. of Surgery, The Royal Infirmary, Sheffield, England, vol. 46, No. 4, pp. 379-386, 1963.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Methods and apparatus for testing disruption of a vagal nerve does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods and apparatus for testing disruption of a vagal nerve, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods and apparatus for testing disruption of a vagal nerve will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3948242

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.