Compounds and method for the treatment of overactive bladder

Details Compounds and method for the treatment of overactive bladder Compounds and method for the treatment of overactive bladder

2008-05-06

2008-05-06

Chang, Celia (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S190000, C546S191000

Reexamination Certificate

active

10494195

ABSTRACT:
NK2R binding compounds in accord with structural diagram I useful for the treatment or prevention of OAB or UI in mammals, particularly humans are disclosed:wherein in said compounds D, A, R1, R3and R4are as defined in the specification. Pharmaceutically-advantageous salts of the compounds, methods of use of the compounds, either alone or in combination with other pharmacological agents, and pharmaceutical compositions useful in practicing the methods of the invention are also disclosed.

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