Surface protein of Neisseria bacteria

Details Surface protein of Neisseria bacteria Surface protein of Neisseria bacteria

2008-04-15

2008-04-15

Zeman, Robert A. (Department: 1645)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Amino acid sequence disclosed in whole or in part; or...

C530S300000, C424S234100, C424S249100

Reexamination Certificate

active

10867662

ABSTRACT:
Present invention provides a monoclonal antibody binding toNeisseriabacteria and its target antigen Ag473, which include the sequences of its polynucleotide and its amino acid, wherein theNeisseriabacteria can beNeisseria meningitidisorNeisseria gonorrhoeae; and wherein Ag473 can be made into a vaccine or a diagnostic or therapeutic reagent.

REFERENCES:
patent: 2005/0260581 (2005-11-01), Fontana et al.
patent: WO 02/079243 (2002-10-01), None
Boslego, J. et al (Gonorrhea Vaccines , Chapter 17, 211-223).
Ellis, R (New Technologies for Making Vaccines, text book, 1998, 568-575).
Danzig, L (MeningococcalVaccines, Pediatr Infect Dis J, 2004; 12 suppl: S285-92), abstract only.
Van Der Ley, P. et al (Construction of a MultivalentMeningococcalVaccine Strain Based On The Class 1 Outer Membrane Protein, Infection and Immunity, 1992; 60(8): 3156-61).
Jones, D (MeningococcalVaccines: Past, Present and Future inMeningococcalDisease, Cartwright, K (ED) Wiley Press, New York, USA, 1995: 147-57).
Perkins, M. et al (Rapid Bacterial Antigen Detection Is Not Clinically Useful, Journal of Clinical Microbiology, 1995; 33(6): 1486-1491).

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