Three dimensional bioengineered smooth muscle tissue and...

Details Three dimensional bioengineered smooth muscle tissue and... Three dimensional bioengineered smooth muscle tissue and...

2008-05-06

2008-05-06

Monshipouri, Maryam (Department: 1656)

Chemistry: molecular biology and microbiology

Apparatus

Differentiated tissue perfusion or preservation apparatus

C600S029000, C435S298200

Reexamination Certificate

active

11286544

ABSTRACT:
This invention relates to a three dimensional bioengineered sphincter such as a bioengineered internal anal sphincter (IAS) and three-dimensional physiological models of smooth muscle cells. The invention also related to methods for generating a bioengineered sphincter and smooth muscle rings in culture. In addition, the invention provides for methods of using a bioengineered sphincter or bioengineered smooth muscle ring to identify agents that modify contractile force and relaxation in smooth muscle cells.

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