Compounds having aromatic rings and side-chain...

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

Reexamination Certificate

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Details

C514S616000, C530S328000, C128S203120, C261SDIG065

Reexamination Certificate

active

10771414

ABSTRACT:
A compound containing at least two aromatic rings covalently bonded together, with each aromatic ring containing at least one oxyacetamide-based side chain, the compound being capable of forming a chloride ion channel across a lipid bilayer, and transporting chloride ion across the lipid bilayer.

REFERENCES:
patent: 5489612 (1996-02-01), Atwood et al.
Sidorov et al, J. Am. Chem. Soc., vol. 124, No. 10, pp. 2267-2278, 2002.
Rivas et al, Proc. Nat. Acad. Sciences, vol. 98, No. 17, pp. 9478-9483, 2001.
Sidorov et al, Chemical Commun., 2000, 2369-2370.
Pellizzi et al, J. Chem. Soc., Perkin Trans. 2, 1998, 1307-1311.
Sidorove et al, IT 325145-46-8P, 2000(see p. 42).
Sidorov et al, Casonline, , pp. 36-42, 2000.
Vladimir Sidorov, et al., “Chloride Anion Transport Across a Lipid Bilayer by an Acyclic Triamide”, Dept. of Chemistry and Biochemistry, University of Md., Oct. 31, 2002, pp. 4-5.
Paul H. Schlesinger, et al., “SCMTR: A Chloride-Selective, Membrane-Anchored Peptide Channel that Exhibits Voltage Gating”, J.Am. Chem. Soc., 2001, pp. 6-7.
Vladimir Sidorov, et al., “Ion Channel Formation from a Calex|4|arene Amide that Binds HCI”, J.Am. Chem. Soc., vol. 124, No. 10, 2002, pp. 8-19.
Vladimir Sidorov, et al., “Chloride Transport Across Lipid Bilayers and Transmembrane Potential Induction by an Oligo-phenoxyacetamide”, Department of Chemistry and Biochemistry, University of Md., , pp. 20-22.

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