Process for preparing reverse transcriptase inhibitors

Details Process for preparing reverse transcriptase inhibitors Process for preparing reverse transcriptase inhibitors

2008-05-27

2008-05-27

Parsa, J. (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

C564S087000

Reexamination Certificate

active

10550255

ABSTRACT:
The present invention is directed to processes for the synthesis of intermediates useful in the preparation of non-nucleoside reverse transcriptase inhibitors.

REFERENCES:
patent: 3828078 (1974-08-01), Mrozik
patent: WO 01/17982 (2001-03-01), None
patent: 02/070470 (2002-09-01), None
Balzarini, “Suppression of resistance to drugs targeted to human immunodeficiency virus reverse transcriptase by combination therapy,”Biochemical Pharmacology58(1):1-27 (Jun. 1999).
De Clercq, “Perspectives of non-nucleoside reverse transcriptase inhibitors (NNRTIs) in the therapy of HIV-1 infection,”Il Famaco54:26-45 (1999).
Wyatt, Paul G., “Benzophenone Derivatives: A Novel Series of Potent and Selective Inhibitors of Human Immunodeficiency Virus Type 1 Reverse Transcriptase.”, J. Med. Chem., 1995, 38, pp. 1657-1665.

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