Statine derivatives for the treatment of Alzheimer's disease

Details Statine derivatives for the treatment of Alzheimer's disease Statine derivatives for the treatment of Alzheimer's disease

2008-04-08

2008-04-08

Davis, Zinna N. (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S270000, C514S617000, C546S328000, C548S190000, C564S152000, C564S153000

Reexamination Certificate

active

11076161

ABSTRACT:
The present invention relates to compounds of formula (I):useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.

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