Pyridoquinoline dopamine agonists, compositions and use

Details Pyridoquinoline dopamine agonists, compositions and use Pyridoquinoline dopamine agonists, compositions and use

1990-04-25

1990-12-11

Ramsuer, Robert W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514212, 514218, 5142328, 514254, 514292, 540470, 540481, 540575, 540597, 544126, 544361, 546 81, A61K 3144, A61K 31535, C07D47104

Patent

active

049771493

ABSTRACT:
Trans-(.+-.)-2-(substituted)-6-(substituted)-5,5a,6,7,8,9,9a,10-octahydropy rido[2,3-g]quinolines are useful in treating a variety of disorders including Parkinsonism, anxiety, depression, hypertension, glaucoma, sexual dysfunction, and prolactin mediated disorders such as galactorrhea, amenorrhea, prolactinoma and the inhibition of postpartum lactation.

REFERENCES:
patent: 3790577 (1974-02-01), Waring
patent: 4198415 (1980-04-01), Kornfeld et al.
patent: 4235909 (1980-11-01), Bach et al.
patent: 4501890 (1985-02-01), Nichols et al.
patent: 4537893 (1985-08-01), Titus et al.
patent: 4659832 (1987-04-01), Schaus et al.
Bach et al., J. Med. Chem., 23, 481, (1980).
Nordman et al., J. Med. Chem., 28(3), 367 (1985).

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