Azasugar compound

Details Azasugar compound Azasugar compound

2007-10-30

2007-10-30

Shameem, Golam M. M. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C548S541000, C514S424000

Reexamination Certificate

active

10726550

ABSTRACT:
The present invention provides a compound represented by the formula (I) or a salt thereof:wherein R1represents a hydrogen atom, a C1-10alkyl group optionally having a substituent, or a protecting group of N; R2represents a C1-10alkyl group optionally having a substituent or a C2-10alkenyl group optionally having a substituent; R3and R4independently represent a hydrogen atom or a protecting group of hydroxyl group; X represents —N(R5)R6or a residue of amino acid or of an amino group of a peptide wherein R5and R6independently represent a hydrogen atom, a C1-10alkyl group optionally having a substituent, or a C3-12cycloalkyl group optionally having a substituent; and Y represents a hydrogen atom, —CH2NH2, —CONH2, or —COOH. The compound of the present invention is useful as a specific inhibitor of sugar chain related enzymes such as glycosyltransferase and glycosidase, and is useful as, for example, a medicine for treating or preventing diseases associated with sugar chain related enzymes.

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