Tumor necrosis factor receptors 6α & 6β

Details Tumor necrosis factor receptors 6α & 6β Tumor necrosis factor receptors 6α & 6β

2007-10-23

2007-10-23

O'Hara, Eileen B. (Department: 1646)

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

C424S133100, C424S138100, C424S139100, C424S141100, C424S143100, C530S387100, C530S387300, C530S387700, C530S387900, C530S388220, C530S350000, C435S007100, C435S007900

Reexamination Certificate

active

09935727

ABSTRACT:
The present invention relates to novel Tumor Necrosis Factor Receptor proteins. In particular, isolated nucleic acid molecules are provided encoding the human TNFR-6α & -6β proteins. TNFR-6α & -6β polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of TNFR-6α & -6β activity. Also provided are diagnostic methods for detecting immune system-related disorders and therapeutic methods for treating immune system-related disorders.

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