Processes for preparing A54145 compounds

Details Processes for preparing A54145 compounds Processes for preparing A54145 compounds

1988-04-11

1990-12-11

Schwartz, Richard A.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Using a micro-organism to make a protein or polypeptide

530317, 514 11, 435896, C12P 2104, A61K 3702, C07K 764

Patent

active

049770837

ABSTRACT:
Improved processes for preparing A54145 components and cyclic peptide derivatives (A54145 compounds) comprising: (1) feeding alkanoic or alkenoic acids or alcohols, or esters or salts thereof, (2) feeding glucose at a rate from about 6-9 g/L/day, or (3) feeding enzymatic soy digest at a rate from about 2-4 g/L/day to an A54145-producing culture during its fermentation and recovering the A54145 compound, are provided.

REFERENCES:
patent: 4208403 (1980-06-01), Hamill et al.
patent: 4331594 (1982-05-01), Hamill et al.
patent: 4356265 (1982-10-01), Hatano et al.
patent: 4396543 (1983-08-01), Debono
patent: 4399067 (1983-08-01), Debono
patent: 4537717 (1985-08-01), Abbott et al.

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