Substituted 5-membered n-heterocyclic compounds and their...

Details Substituted 5-membered n-heterocyclic compounds and their... Substituted 5-membered n-heterocyclic compounds and their...

2007-08-28

2007-08-28

Saeed, Kamal A. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S342000, C546S269700, C548S201000

Reexamination Certificate

active

10498104

ABSTRACT:
This invention relates to substituted 5-membered N-Herterocyclic neurotrophic compounds of formula (I) or pharmaceutically acceptable salts or hydrates thereof, wherein R1, R2, R3, R4, V, W, X, Y, and Z are as defined in the description; their preparation methods, compositions comprising the same, and their use as inhibitors of FK560 binding proteases (FKBPs) activity for treating and preventing neurodegenerative diseases and other nerve disorders associated with nerve injuries or other related diseases.

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Dunkerton et al. Tetrahedron Letters 1980, 21(19), 1803-6 *CAS Abstract provided.

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