Compositions useful as inhibitors of JAK and other protein...

Details Compositions useful as inhibitors of JAK and other protein... Compositions useful as inhibitors of JAK and other protein...

2007-12-25

2007-12-25

Balasubramanian, Venkataraman (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C544S330000, C544S331000, C544S180000, C544S181000, C544S238000, C514S241000, C514S242000, C514S252010

Reexamination Certificate

active

10700333

ABSTRACT:
The present invention provides a compound of formula I:or a pharmaceutically acceptable salt thereof. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of utilizing those compounds and compositions in the treatment of various protein kinase mediated disorders.

REFERENCES:
patent: 6949544 (2005-09-01), Bethiel et al.
patent: 2004/0176271 (2004-09-01), Bethiel et al.
patent: WO 95/09847 (1995-04-01), None
patent: WO 95/09851 (1995-04-01), None
patent: WO 95/09853 (1995-04-01), None
patent: WO 97/19065 (1997-05-01), None
patent: WO 99/65897 (1999-12-01), None
patent: WO 01/29009 (2001-04-01), None
patent: WO-02/20495 (2002-03-01), None
patent: WO 02/22601 (2002-03-01), None
patent: WO 02/46170 (2002-06-01), None
patent: WO 02/46171 (2002-06-01), None
patent: WO 02/079193 (2002-10-01), None
patent: WO 02/079197 (2002-10-01), None
patent: WO 03/030909 (2003-04-01), None
Cecil Textbook of Medicine, edited by Bennet, J.C., and Plum F., 20th edition,vol. 1, 1004-1010, 1996.
Duhe et al. Cell Biochem. Biophys. 34(1): 17-59, 2001.
Rane et al., Oncogene 19(49): 5662-79, 2000.
Ivashkiv et al., Arthritis & Rheumatism 48(8)2092-2096, 2003.
Changelian et al., “Prevention of organ allograft rejection by a specific janus kinase 3 inhibitor,” Science, 302:875-878, (2003).
Malaviya et al., “Treatment of allergic asthma by targeting janus kinase 3-dependent leukotriene synthesis in mast cells with 4-(3′,5′—dibromo-4′-hydroxyphenyl)amino-6,7-dimethoxyquinazoline (WHI-P97),” The Journal of Pharmacology and Experimental Therapeutics, 295(3):912-926, (2000).
Trieu et al., “A specific inhibitor of janus kinase-3 ncreases survival in a transgenic model of amyotrophic lateral sclerosis,” Biochemical and Biophysical Research Communications, 267:22-25, (2000).

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