Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2007-08-07
2007-08-07
Huff, Sheela J. (Department: 1643)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C436S536000, C435S975000
Reexamination Certificate
active
10721434
ABSTRACT:
An immunological assay and kit for colon cancer screening is disclosed. Fecal glycoproteins are extracted from individual samples such that immunogenicity is maintained. The purified fecal glycoproteins are reacted with antibodies to Colon and Ovarian Tumor Antigen (COTA). The mucin antigen COTA is specifically present in colorectal cancer tissue and not in normal colons. The amount of COTA in the fecal sample is determined and used to indicate the presence of colon cancer.
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Fagoaga Omar
Kelln Wayne
McCracken John D.
Nehlsen-Cannarella Sandra
Pant Keshab D.
Huff Sheela J.
Knobbe Martens Olson & Bear LLP
Loma Linda University Adventist Health Sciences Center
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