Dipeptidyl peptidases

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase

Reexamination Certificate

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Reexamination Certificate

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10415122

ABSTRACT:
Peptides including HisGlyTrpSerTyrGlyGlyPheLeu; LeuAspGluAsnValHisPhePhe; GluArgHisSerIle Arg and PheValIleGlnGluGluPhe which show peptidase ability and have substrate specificity for at least one of the compounds H-Ala-Pro-pNA, H-Gly-Pro-pNA and H-Arg-Pro-pNA are disclosed. Nucleic acids, vectors, antibodies and hybridoma cells are also claimed with reference to the above sequences and their abilities.

REFERENCES:
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patent: 2002/0197679 (2002-12-01), Tang et al.
patent: 2004/0132158 (2004-07-01), Bandman et al.
patent: 2005/0101529 (2005-05-01), Yue et al.
patent: WO 01/19866 (2001-03-01), None
patent: WO200153312 (2001-07-01), None
patent: WO200231134 (2002-04-01), None
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Pub—Applications—AA—Main US20050101529 priority date Dec. 8, 2000 Qi et al SEQ ID No. 12. Alignment with SEQ ID No. 4.
Ajami et al, Dipeptidyl peptidase 9 has two forms, a broad tissue distribution, cytoplasmic localization and DPIV-like peptidase activity. Biochim Biophys Acta. Jul. 13, 2004;1679(1):18-28.
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GenPept AAH00970 Strausberg et al, mRNA, Partial CDS (Submitted Nov. 16, 2000) Jul. 12, 2001.

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