Substituted 3-cyanoquinolines as MEK inhibitors

Details Substituted 3-cyanoquinolines as MEK inhibitors Substituted 3-cyanoquinolines as MEK inhibitors

2007-02-06

2007-02-06

Seaman, D. Margaret (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C546S159000, C514S311000, C514S312000, C514S313000

Reexamination Certificate

active

10520468

ABSTRACT:
The invention concerns quinoline derivatives of Formula (I) wherein each of Z1, m, R1, n, R3, Z2and R14have any of the meanings defined hereinbefore in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an anti-invasive or anti-proliferative agent in the containment and/or treatment of solid tumour disease.

REFERENCES:
patent: 3376195 (1968-04-01), Allais et al.
patent: 3936461 (1976-02-01), Schwender et al.
patent: 4421920 (1983-12-01), Baudouin et al.
patent: 5409930 (1995-04-01), Spada et al.
patent: 5650415 (1997-07-01), Tang et al.
patent: 5656643 (1997-08-01), Spada et al.
patent: RE36256 (1999-07-01), Spada et al.
patent: 6002008 (1999-12-01), Wissner et al.
patent: 6630489 (2003-10-01), Crawley
patent: 6638945 (2003-10-01), Gibson
patent: 6809106 (2004-10-01), Gibson
patent: 0326330 (1989-08-01), None
patent: 0607439 (1994-07-01), None
patent: 2077455 (1969-09-01), None
patent: WO 93/03030 (1993-02-01), None
patent: WO 96/09294 (1996-03-01), None
patent: WO 97/03069 (1997-01-01), None
patent: WO 97/17329 (1997-05-01), None
patent: WO 98/02434 (1998-01-01), None
patent: WO 99/35146 (1999-07-01), None
patent: 00/18761 (2000-04-01), None
patent: WO 00/18761 (2000-04-01), None
patent: WO 00/68199 (2000-11-01), None
patent: WO 00/68200 (2000-11-01), None
patent: WO 00/68201 (2000-11-01), None
patent: WO 01/94341 (2001-12-01), None
patent: WO 02/16352 (2002-02-01), None
patent: WO 02/36570 (2002-05-01), None
patent: WO 02/44166 (2002-06-01), None
patent: WO 02/085895 (2002-10-01), None
patent: 03/008409 (2003-01-01), None
patent: WO 03/008409 (2003-01-01), None
patent: WO 03/047582 (2003-06-01), None
patent: WO 03/047583 (2003-06-01), None
patent: WO 03/047585 (2003-06-01), None
patent: WO 03/053960 (2003-07-01), None
patent: WO 2004/004732 (2004-01-01), None

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