Nucleic acid labeling compounds

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C536S022100, C536S024200, C536S025300, C435S006120

Reexamination Certificate

active

10452519

ABSTRACT:
Nucleic acid labeling compounds containing heterocyclic derivatives are disclosed. The heterocyclic derivative containing compounds are synthesized by condensing a heterocyclic derivative with a cyclic group (e.g. a ribofuranose derivative). The labeling compounds are suitable for enzymatic attachment to a nucleic acid, either terminally or internally, to provide a mechanism of nucleic acid detection.

REFERENCES:
patent: 3352849 (1967-11-01), Shen et al.
patent: 3817837 (1974-06-01), Rubenstein et al.
patent: 3850752 (1974-11-01), Schuurs et al.
patent: 389162 (1975-06-01), Vorbruggen et al.
patent: 3891623 (1975-06-01), Vorbruggen
patent: 3939350 (1976-02-01), Kronick et al.
patent: 3996345 (1976-12-01), Ullman et al.
patent: 4275149 (1981-06-01), Litman et al.
patent: 4277437 (1981-07-01), Maggio
patent: 4366241 (1982-12-01), Tom et al.
patent: 4594339 (1986-06-01), Lopez et al.
patent: 4981783 (1991-01-01), Augenlicht
patent: 4997928 (1991-03-01), Hobbs, Jr.
patent: 5002867 (1991-03-01), Macevicz
patent: 5143854 (1992-09-01), Pirrung et al.
patent: 5151507 (1992-09-01), Hobbs, Jr. et al.
patent: 5173260 (1992-12-01), Zander et al.
patent: 5202231 (1993-04-01), Drmanac et al.
patent: 5242796 (1993-09-01), Prober et al.
patent: 5262536 (1993-11-01), Hobbs, Jr.
patent: 5324633 (1994-06-01), Fodor et al.
patent: 5332666 (1994-07-01), Prober et al.
patent: 5422241 (1995-06-01), Goldrick et al.
patent: 5424186 (1995-06-01), Fodor et al.
patent: 5445934 (1995-08-01), Fodor et al.
patent: 5543292 (1996-08-01), Imai et al.
patent: 5571639 (1996-11-01), Hubbell et al.
patent: 5608063 (1997-03-01), Hobbs, Jr. et al.
patent: 5744305 (1998-04-01), Fodor et al.
patent: 6174998 (2001-01-01), Muhlegger et al.
patent: 6211158 (2001-04-01), Seela et al.
patent: 6403786 (2002-06-01), Muhlegger et al.
patent: 6596856 (2003-07-01), McGall et al.
patent: 6844433 (2005-01-01), McGall et al.
patent: 6864059 (2005-03-01), McGall et al.
patent: 6965020 (2005-11-01), McGall et al.
patent: 19509038 (1996-09-01), None
patent: 0132621 (1985-02-01), None
patent: 0159719 (1985-10-01), None
patent: 0252683 (1988-01-01), None
patent: 0266787 (1988-05-01), None
patent: 0320308 (1989-06-01), None
patent: 0322311 (1989-06-01), None
patent: 0336731 (1989-10-01), None
patent: 0535242 (1993-04-01), None
patent: 0717113 (1996-06-01), None
patent: 0721016 (1996-07-01), None
patent: 61-109797 (1986-05-01), None
patent: WO-89/10977 (1989-11-01), None
patent: WO-90/00626 (1990-01-01), None
patent: WO-90/03370 (1990-04-01), None
patent: WO-90/04652 (1990-05-01), None
patent: WO-90/15070 (1990-12-01), None
patent: WO-92/02258 (1992-02-01), None
patent: WO-92/10092 (1992-06-01), None
patent: WO-92/10588 (1992-06-01), None
patent: WO-93/16094 (1993-08-01), None
patent: WO-93/17126 (1993-09-01), None
patent: WO-95/00530 (1995-01-01), None
patent: WO-95/04594 (1995-02-01), None
patent: WO-95/04833 (1995-02-01), None
patent: WO-95/04834 (1995-02-01), None
patent: WO-95/11995 (1995-05-01), None
patent: WO-95/20681 (1995-08-01), None
patent: WO-95/30774 (1995-11-01), None
patent: WO-95/35505 (1995-12-01), None
patent: WO-96/28460 (1996-09-01), None
patent: WO-97/10365 (1997-03-01), None
patent: WO-97/27317 (1997-07-01), None
patent: WO-97/28176 (1997-08-01), None
patent: WO-97/29212 (1997-08-01), None
patent: WO-97/39120 (1997-10-01), None
patent: WO-98/11104 (1998-03-01), None
patent: WO-00/06771 (2000-02-01), None
Akita, Y., et al., “Cross-Coupling Reaction of Chloropyrazines with Acetylenes”,Chemical&Pharmaceutical Bulletin, 34 (4), (Apr. 1986),pp. 1447-1458.
Aoyagi, M., et al., “Nucleosides and Nucleotides. 115. Synthesis of 3-Alkyl-3-Deazainosines via Palladium-Catalyzed Intramolecular Cyclization: A New Conformational Lock with the Alkyl Group at the 3-Position of the 3-Deazainosine in Anti-Conformation”,Tetrahedron Letters, 34 (1), (1993),pp. 103-106.
Aoyagi, M., et al., “Nucleosides and Nucleotides. 115. Synthesis of 3-Alkyl-3-Desainosines”,Tetrahedron Letters, 34 (1), (1993), 103-106.
Avila, J. L., et al., “Biological Action of Pyrazolopyrimidine Derivatives Against Trypanosoma Cruzi. Studies In Vitro and In Vivo”,Comp. Biochem. Physiol., 86C (1), (1987),pp. 49-54.
Avila, J. L., et al., “Biological action of Pyrazolopyrimidine Detrivates Against . . . ”,Comp. Biochem. Physiol., 86C (1), (1987),49-54.
Barringer, et al., “Blunt-end and single-strand legations byEscherichia coliligase . . . ”,Gene, 89, (1990),177-122.
Barringer, et al., “Blunt-end and single-strand ligations byEscherichia coliligase: influence on an in vitro amplification scheme”,Gene, 89, (1990), pp. 117-122.
Basnak, I. et al., “Some 6-Aza-5-Substituted-2′ -Deoxyuridines Show Potent and . . . ”,Nucleosides and Nucleotides, 17 (1 1-3), (1998), 187-206.
Basnak, I., et al., “Some 6-Aza-5-Substituted-2′-Deoxyuridines Show Potent and Selective Inhibition of Herpes Simplex Virus Type 1 Thymidine Kinase”,Nucleosides&Nucleotides, 17 (1-3), (1998),pp. 187-206.
Beabealashvilli, R. S., et al., “Nucleoside 5'-triphosphates modified at sugar residues as substrates for calf thymus terminal deoxynucleotidyl transferase and for AMV reverse transcriptase”,Biochimica et Biophysica Acta, 868, (1986),pp. 136-144.
Beabealashvilli, R. S., et al., “Nucleoside 5′-triphosphates modified at sugar residues . . . ”,Biochemica et Biophysica Acta, 868, (1986),pp. 136-144.
Bergerin, et al., “Reagents for the stepwise functionalization of spermine”,J. Org. Chem., 53, (1998),3108-3111.
Bergeron, et al., “Reagents for the stepwise functionalization of spermine”,J. Org. Chem., 53, (1998),pp. 3108-3111.
Bergstrom, D. E., et al., “Design and Synthesis of Heterocyclic Carboxamides as Natural Nucleic Acid Base Mimics”,Nucleosides&Nucleotides, 15 (1-3), (1996), pp. 59-68.
Bergstrom, D. E., et al., “Design and Synthesis of Heterocyclic Carboxamides as Natural . . . ”,Nucleosides and Nucleotides, 15 (1-3), (1996),59-68.
Bobek, M., et al., “Nucleic Acids Components and their Analogues. XCVII. Synthesis of 5-Hydroxymethyl-6-Aza-2′- Deoxyuridine and 5-Hydroxymethyl-6-Aza-2′-Deoxycytidine”,Collection Czechoslov. Chem. Commun., 32, (1967), pp. 3581-3586.
Bobek, M., et al., “Nucleic Acids Components and their Analogues . . . ”,Collection Czechoslov. Chem. Commun., 32, (1967),3581-3586.
Brody, R. S., et al., “The Purification of Orotidine-5′-phosphate Decarboxylase from . . . ”,The Journal of Biological Chemistry, 254 (10), (1979),4238-4244.
Brody, R. S., et al., “The Purification of Orotidine-5′-phosphate Decarboxylase from Yeast by Affinity Chromatography”,The Journal of Biological Chemistry, 254 (10), (1979),pp. 4238-4244.
Broude, N.E., et al., “Enhanced DNA sequencing by hyridization”,PNAS, 91, (1994),3072-3076.
Canard, B., et al., “Catalytic editing properties of DNA Polymerases”,PNAS, 91, (1995), 10859-10863.
Canard, B., et al., “Catalytic editing properties of DNA polymerases”,PNAS, 92, (Nov. 1995),pp. 10859-10863.
Cech, D., et al., “New Approaches Toward the Synthesis of Non-Radioactively Labelled Nucleoside Triphosphates as Terminators for DNA Sequencing”,Collect. Czech. Chem. Commun., 61, Special Issue,(1996),pp. S297-S300.
Cech, D., et al., “New Approaches Toward the Synthesis of Non-Radioactively . . . ”,Collect. Czech. Chem. Commun., 61,(1996),S297-S300.
Chee, M., “Accessing Genetic Information with High-Density DNA Arrays”,Science, 274, (1996),610-614.
Chee, M., et al., “Accessing Genetic Information with High-Density DNA Arrays”,Science, 274, (Oct. 25, 1996),pp. 610-614.
Chernetskii, V. P., et al., “Anomalous nucleosides and related compounds, XIV, Derivatives of 6-azacytidine.”,Chemical Abstracts, 74 (21), Abstract No. 112367j,(1971).
Chernetskii, V.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Nucleic acid labeling compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Nucleic acid labeling compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nucleic acid labeling compounds will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3883641

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.