Methods and compositions for blocking microbial adherence to...

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Capsules

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C424S464000, C424S489000

Reexamination Certificate

active

10053299

ABSTRACT:
A method of blocking microbial adherence to a eukaryotic cell surface in a mammal by applying a pharmacologically acceptable composition containing at least one compound selected from the group consisting of isoleucine, an active isomer thereof, and an active analog thereof, to said surface in a microbial blocking quantity. Also, compositions for achieving the above blocking of microbial adherence.

REFERENCES:
patent: 6388056 (2002-05-01), Sundstrom et al.
patent: 6607711 (2003-08-01), Pedersen
patent: 6770306 (2004-08-01), Zeng
Webster's New Collegiate Dictionary 41 (1976).
The Merck Index, An encyclopedia of Chemicals, Drugs, and Biologicals 883 (12thed. 1996).
Arvola T., Laiho K, Torkkeli S, Mykkanen H., Salminem S., Maumula L, and Isolauri E. Prophylactic Lactobacilius GG reduces antibiotic-associated diarrhea in children with respiratory infections:a randomized study. Pediatrics 104, e64, 1999.
Boris S and Barbes C. Role played by lactobacilli in controlling the population of vaginal pathogens. Microbes Infect. 2, 543-546, 2000.
Brighenti F, Casiraghi MC, Canzi E, and Ferrari A. Effect of consumption of a ready-to eat breakfast cereal containing inulin on the intestinal milieu and blood lipids in healthy male volunteers. European Journal of Clinical Nutrition 53, 726-733, 1999.
Du Toit M, Franz CM, Dicks, LM, Schillinger U., Haberer P, Warlies B., Ahrens F, and Holzapfel W.H. Characterization and selection of probiotic lactobacilli for a preliminary minipig feeding trial and their effect on serum cholesterol levels, faeces pH and faeces moisture content. Int. J. Food Microbiol. 40, 93-104, 1998.
Gionchetti P., Rizzello F., Venturi A., Brigidi P., Matteuzzi D, Bazzocchi , Poggioli G., Miglioli M., and Campieri M. Oral bacteriotherapy as a maintenance treatment in patients with chronic pouchitis: a double-blind, placebo-controlled trial. Gastroenterology 119, 305-309, 2000.
Guanalini S, Pensabebene L, Zikri MA, Dias JA, Casali LG, Hoekstra , Kolacek S, Massar K, Micetic-Turk D, Papadopoulou A, de Sousa JS, Sandhu B, Szajewska H, Weizman Z. Lactobacillus GG administered in oral rehydration solution to children with acute diarrhea: a multicenter European trial. J. Pediatr. Gastroenterol. Nutr. 30. 54-60, 2000.
Kelly CG and Younson JS. Anti-adhesive strategies in the prevention of infectious disease at mucosal surfaces. Expert Opin. Investig. Drugs 9, 1711-1721, 2000.
Martin H.L., Richardson, B.A., Nyange, P.M., Lavreys, L., Hillier S.L., Chohan B., Mandaliya K., Ndinya-Achola J.O., Bwayo J. and Kreiss J. Vaginal lactobacilli, microbial flora, and risk of human immunodeficiency virus type 1 and sexulally transmitted disease acquisition. J. Infect. Dis. 180,1863-1868, 1999.
Merz AJ and So M. Interactions of pathogenicNeisseriaewith epithelial cell membranes. Annu. Rev. Cell. Dev. Biol. 16, 423-457, 2000.
Mohan B., Kadirvel A., Natarajan A. and Bhaskaran M. Effect of probiotic supplementation on growth, nitrogen utilization and serum cholesterol in broilers. British Poultry Science 37, 395-401, 1996.
Mulvey MA, Schilling JD, Martinez JJ, Hultgren, SJ. From the cover: bad bugs and releagered bladders: interplay between uropathogenicEscherichia coland innate host defenses. Proc. Natl. Acad. Sci. USA 97, 8829-8835, 2000.
Nobaek S., Johansson M-L., Molin G., Ahrne S., and Jeppsson B. Alteration of intestinal microflora is associated with a reduction in abdominal bloating and pain in patients with irritable bowel syndrome. American Journal of Gastroenterology 1231-1238, 2000.
Petro T.M and Bhattacharjee J.K. Effect of dietary amino acid limitations upon native levels of murine immunoglobulins, transferrin, and complement. Infect. Immun. 27, 513-518, 1980.
Petro T.M and Bhattacharjee J.K. Effect of dietary amino acid limitations upon the susceptibility toSalmonella typhimuriumand the effect upon humoral and cellular immune responses in mice. Infect. Immun. 32, 251-259, 1981.
Reid, G. Potential preventive strategies and therapies in urinary tract infection. World J. Urol. 17, 359-363, 1999.
Sobel, J. Bacterial Vaginosis. Annu. Rev. Med. 51, 349-356, 2000.
Vanderhoof JA, Whitney DB, Antonson DL, Hanner TL, Lupo JV, and Young, RJ. Lactobacillus GG in the prevention of antibiotic-associated diarrhea in children. Journal of Pediatrics 135: 564-568, 1999.
Venturî A., Gionchetti P., Rizzello F., Johansson R., Zucconi E., Brigidi P., Matteuzzi D., and Campieri M. Impact on the composition of the faecal flora by a new probiotic preparation: preliminary data on maintenance treatment of patients with ulcerative colitis. Aliment. Pharmacol. Ther. 13, 1103-1108, 1999.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Methods and compositions for blocking microbial adherence to... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods and compositions for blocking microbial adherence to..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods and compositions for blocking microbial adherence to... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3873449

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.