Bone graft substitute composition

Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Implantable prosthesis – Bone

Reexamination Certificate

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C623S023510, C623S023610, C623S016110, C424S549000, C424S682000, C424S696000

Reexamination Certificate

active

10448885

ABSTRACT:
Bone graft substitute compositions and methods of making the compositions are disclosed. In some embodiments, a method of making a composition includes contacting a mixing solution with a first mixture having calcium sulfate hemihydrate and a plasticizing material to form a second mixture; waiting a predetermined period of time after forming said second mixture; and then contacting demineralized bone with the second mixture to form the composition. A composition can be formed from a kit including a first mixture having calcium sulfate hemihydrate and a plasticizing substance, a second mixture having demineralized bone, and a mixing solution. The first and second mixtures and the mixing solution are unblended.

REFERENCES:
patent: 3813312 (1974-05-01), Kinkade et al.
patent: 4430760 (1984-02-01), Smestad
patent: 4568536 (1986-02-01), Kronenthal et al.
patent: 4595713 (1986-06-01), St. John
patent: 4596574 (1986-06-01), Urist
patent: 4612009 (1986-09-01), Drobnik et al.
patent: 4619655 (1986-10-01), Hanker et al.
patent: 4650665 (1987-03-01), Kronenthal et al.
patent: 4681763 (1987-07-01), Nathanson et al.
patent: 4820306 (1989-04-01), Gorman et al.
patent: 4880660 (1989-11-01), Aasen et al.
patent: 4882149 (1989-11-01), Spector
patent: 4892734 (1990-01-01), Leonard
patent: 4975526 (1990-12-01), Kuberasampath et al.
patent: 4994030 (1991-02-01), Glowczewskie, Jr. et al.
patent: 5061286 (1991-10-01), Lyle
patent: 5073373 (1991-12-01), O'Leary et al.
patent: 5147403 (1992-09-01), Gitelis
patent: 5162114 (1992-11-01), Kuberasampath et al.
patent: 5219897 (1993-06-01), Murray
patent: 5236456 (1993-08-01), O'Leary et al.
patent: 5236971 (1993-08-01), Murray
patent: 5264214 (1993-11-01), Rhee et al.
patent: 5284655 (1994-02-01), Bogdansky et al.
patent: 5290558 (1994-03-01), O'Leary et al.
patent: 5298254 (1994-03-01), Prewett et al.
patent: 5306304 (1994-04-01), Gendler
patent: 5314476 (1994-05-01), Prewett et al.
patent: 5320844 (1994-06-01), Liu
patent: 5336699 (1994-08-01), Cooke et al.
patent: 5356629 (1994-10-01), Sander et al.
patent: 5366507 (1994-11-01), Sottosanti
patent: 5385887 (1995-01-01), Yim et al.
patent: 5405390 (1995-04-01), O'Leary et al.
patent: 5417975 (1995-05-01), Lussi et al.
patent: 5425769 (1995-06-01), Snyders, Jr.
patent: 5439684 (1995-08-01), Prewett et al.
patent: 5462722 (1995-10-01), Liu et al.
patent: 5482551 (1996-01-01), Morris et al.
patent: 5484601 (1996-01-01), O'Leary et al.
patent: 5507813 (1996-04-01), Dowd et al.
patent: 5510396 (1996-04-01), Prewett et al.
patent: 5512610 (1996-04-01), Lin
patent: 5531791 (1996-07-01), Wolfinbarger, Jr.
patent: 5569308 (1996-10-01), Sottosanti
patent: 5573771 (1996-11-01), Geistlich et al.
patent: 5578662 (1996-11-01), Bennett et al.
patent: 5614206 (1997-03-01), Randolph et al.
patent: 5618549 (1997-04-01), Patat et al.
patent: 5676146 (1997-10-01), Scarborough
patent: 5681873 (1997-10-01), Norton et al.
patent: 5697981 (1997-12-01), Ison et al.
patent: 5700289 (1997-12-01), Breitbart et al.
patent: 5707962 (1998-01-01), Chen et al.
patent: 5727945 (1998-03-01), Dannenbaum
patent: 5756127 (1998-05-01), Grisoni et al.
patent: 5763416 (1998-06-01), Bonadio et al.
patent: 5766618 (1998-06-01), Laurencin et al.
patent: 5769897 (1998-06-01), Harte
patent: 5788976 (1998-08-01), Bradford
patent: 5807567 (1998-09-01), Randolph et al.
patent: 5824087 (1998-10-01), Aspden et al.
patent: 5830493 (1998-11-01), Yokota et al.
patent: 5861445 (1999-01-01), Xu et al.
patent: 5899939 (1999-05-01), Boyce et al.
patent: 5910315 (1999-06-01), Stevenson et al.
patent: 5948426 (1999-09-01), Jefferies
patent: 5948428 (1999-09-01), Lee et al.
patent: 5964805 (1999-10-01), Stone
patent: 5972368 (1999-10-01), McKay
patent: 5981828 (1999-11-01), Nelson et al.
patent: 6030635 (2000-02-01), Gertzman et al.
patent: 6030636 (2000-02-01), Randolph et al.
patent: 6037519 (2000-03-01), McKay
patent: 6051247 (2000-04-01), Hench et al.
patent: 6056970 (2000-05-01), Greenawalt et al.
patent: 6071530 (2000-06-01), Polson et al.
patent: 6083522 (2000-07-01), Chu et al.
patent: 6118043 (2000-09-01), Nies et al.
patent: 6224635 (2001-05-01), Ricci et al.
patent: 6340477 (2002-01-01), Anderson
patent: 6409823 (2002-06-01), Shake et al.
patent: 6478825 (2002-11-01), Winterbottom et al.
patent: 6652887 (2003-11-01), Richelsoph et al.
patent: 2002/0016636 (2002-02-01), Ricci et al.
patent: 2002/0071827 (2002-06-01), Petersen et al.
patent: 2002/0110541 (2002-08-01), Petersen
patent: 2003/0050710 (2003-03-01), Petersen et al.
patent: 2003/0143258 (2003-07-01), Knaack et al.
patent: 2003/0185903 (2003-10-01), Cole et al.
patent: 2003/0235621 (2003-12-01), Miller et al.
patent: 196 20 117 (1997-07-01), None
patent: 2 093 348 (1982-09-01), None
patent: WO89/04646 (1989-06-01), None
patent: 91/00252 (1991-01-01), None
patent: WO96/39203 (1996-12-01), None
patent: WO98/40113 (1998-09-01), None
patent: WO99/15150 (1999-04-01), None
patent: WO 00/74690 (2000-12-01), None
patent: WO 00/74690 (2000-12-01), None
patent: WO 02/05750 (2002-01-01), None
patent: WO 03/024316 (2003-03-01), None
patent: WO 03/030956 (2003-04-01), None
patent: WO 03/045455 (2003-06-01), None
Advances in Biomaterials for Bone Regeneration, Orthopedics, vol. 26, No. 5/Supplement, May 2003.
Randal R. Betz, M.D., “Limitations of Autograft and Allograft: New Synthetic Solutions”, Orthopedics, vol. 25, No. 5, Supplement May 2002.
“Bone Graft Substitutes Safe, Effective”, AMA Science News Media Briefings, Dec. 6, 2001.
Turner et al., “Radiographic and Histologic Assessment of Calcium Sulfate in Experimental Animal Models and Clinical use as a Resorbable Bone-Graft Substitute, A Bone-Graft Expander, and a Method for Local Antibiotic Delivery”, The Journal of Bone and Joint Surgery, Incorporated, vol. 83-A, Supp. 2, Part 1, 2001.
Greenwald et al., “Bone-Graft Substitutes: Facts, Fictions, and Applications”, The Journal of Bone & Joint Surgery, JBJS Org., vol. 83-A, Supplement 2, Part 2, 2001.
Evelyn B. Kelly, Ph.D., “New Frontiers in Bone Grafting”, Orthopaedic Technology Review, vol. 2, No. 9, Oct. 2000.
Adkisson et al., “Rapid Quantitative Bioassay of Osteoinduction”, Journal of Orthopaedic Research, 18:503-511, 2000.
Hanker et al., “Setting of Composite Hydroxylaptie/Plaster Implants with Blood for Bone Reconstruction,” Proceedings of the 44thAnnual Meeting of the Electron Microscopy Society of America, 1986.
Biomaterials Tutorial, www.btec.cmu.edu/tutorial/biomaterials/biomaterials.htm, Undated.
Grimandi et al., “In vitro evaluation of a new injectable calcium phosphate material”,J. Biomed. Mater Res., 1998, pp. 660-666, vol. 39, John Wiley & Sons, Inc.
Anson, D., “Saving Periodontally ‘Hopeless Teeth’ Using Calcium Sulfate and Demineralized Freeze-Dried Bone Allograft”,Compendium, 1998, pp. 284-298, vol. 19, No. 3.

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