Phenylaminopyrimidine derivatives and methods of use

Details Phenylaminopyrimidine derivatives and methods of use Phenylaminopyrimidine derivatives and methods of use

2007-06-19

2007-06-19

Rao, Deepak (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S275000, C544S331000

Reexamination Certificate

active

10821382

ABSTRACT:
The present invention relates to phenylaminopyrimidine derivatives, processes for their preparation, pharmaceutical compositions containing them as active ingredient, methods for the treatment of disease states such as cancers associated with tyrosine kinases, especially Bcr-Abl, to their use as medicaments and to their use in the manufacture of medicaments for use in the production of inhibition of tyrosine kinase reducing effects in warm-blooded animals such as humans.

REFERENCES:
patent: WO 2004/029038 (2004-04-01), None
patent: WO 2004/099186 (2004-11-01), None
Ulrich, Chapter 4: Crystallization, Kirk-Othmer Encyclopedia of Chemical Technology, Aug. 2002.
Vippagunta et al., Cyrstalline Solids, Advanced Drug Delivery Reviews, 48, pp. 3-26, 2001.
West, Solid Solutions, Solid State Chemistry and its applications, pp. 358 & 365, 1988.

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