Polypeptide uder-expressed in melanoma

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

Reexamination Certificate

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C530S387300

Reexamination Certificate

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10063560

ABSTRACT:
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

REFERENCES:
patent: 5546637 (1996-08-01), Jacobs
patent: 6025156 (2000-02-01), Gwynn et al.
patent: 6124433 (2000-09-01), Falb et al.
patent: 6156500 (2000-12-01), Falb
patent: 6162604 (2000-12-01), Jacob
patent: 6204371 (2001-03-01), Levinson
patent: 6228582 (2001-05-01), Rodier et al.
patent: 6395306 (2002-05-01), Cui et al.
patent: 6414117 (2002-07-01), Levinson
patent: 6465185 (2002-10-01), Goldfine et al.
patent: 6498235 (2002-12-01), Sheppard et al.
patent: 6534641 (2003-03-01), Falb et al.
patent: 6562343 (2003-05-01), Levinson
patent: 6645499 (2003-11-01), Lal et al.
patent: 6730502 (2004-05-01), Van Hijum et al.
patent: 6737522 (2004-05-01), Sundick et al.
patent: 2003/0027275 (2003-02-01), Baker et al.
patent: 2003/0073129 (2003-04-01), Baker et al.
patent: WO 97/38085 (1997-10-01), None
patent: WO 99/55721 (1999-11-01), None
patent: 00/77037 (2000-05-01), None
patent: WO 00/61623 (2000-10-01), None
patent: WO 01/68848 (2001-09-01), None
GenCore version 5.1.6, © 1993-2004, us-10-0060867-52.rapb, see Result 1 summary and alignment.
Haynes et al. (1998, Electrophoresis 19:1862-1871).
Lewin, Genes VI (1997) Chapter 29, pp. 847-848.
Gokman-Polar et al (Cancer Research 61:1375-1381, 2001).
Pennica et al (PNAS, 95:14717-22, 1998).
Hu et al. (2003, Journal of Proteome Research 2:405-412).
Konopka et al (PNAS, 83:4049-52, 1986).
McGuinness et al. (Mol. Microbiol. 7: 505-514, Feb. 1993).
Houghten et al. (New Approaches to Immunization, Vaccines86, Cold Spring Harbor Laboratory, p. 21-25, 1986).
McGuinness et al. (Lancet 337: 514-517, Mar. 1991).
Gronborg et al (Molecular and Cellular Proteomics, 2006 Abstract only).
Herbert et al eds, The Dictionary Immunology, Fourth Edition, Academic Press, 1995, p. 147.
Lederman et al. (Molecular Immunology 28: 1171-1181, 1991).
Li et al. (PNAS 77: 3211-3214, 1980).
Klein et al. Selection for Genes Encoding Secreted Proteins and Receptors.Proc. Natl. Acad. Sci., 93:7108-7113 (1996).
Database Search, DNA Sequence Alignments [BLASTN 2.2.1[Jul. 12, 2001], NCBI].
Database Search, Protein Sequence Alignments [BLASTN 2.2.1 [Jul. 12, 2001], NCBI].
Alberts, et al. 1994.Molecular Biology of the Cell, 3rd Edition, pp. 403-404, 453. New York: Garland Publishing.
Alberts, et al. 2002.Molecular Biology of the Cell 4th Edition, pp. 302, 363-364, 379, 435. New York: Garland Publishing.
Grimaldi, et al. 1989. The t(5;14) chromosomal translocation in a case of acute lymphocytic leukemia joins the interleukin-3 gene to the immunoglobulin heavy chain gene.Blood, 73(8):2081-2085.
Gygi, et al. 1999. Correlation between protein and mRNA abundance in yeast.Molecular and Cellular Biology, 19(3):1720-1730.
Hanna, et al. Aug. 1999. HER-2
eu breast cancer predictive testing.Pathology Associates Medical Laboratories.
Hyman, et al. 2002. Impact of DNA amplification on gene expression patterns in breast cancer.Cancer Research, 62:6240-6245.
Lewin, B. 1997. Regulation of Transcription, Chap. 29, pp. 847-848.Genes VI. New York: Oxford University Press.
Meeker, et al. 1990. Activation of the interleukin-3 gene by chromosome translocation in acute lymphocytic leukemia with eosinophilia.Blood, 76(2):285-289.
Meric, et al. 2002. Translation initiation in cancer: A novel target for therapy.Molecular Cancer Therapeutics, 1: 971-979.
Ørntoft, et al. 2002. Genome-wide study of gene copy Nos., transcripts, and protein levels in pairs of non-invasive and invasive human transitional cell carcinomas.Molecular&Cellular Proteomics, 1:37-45.
Pollack, et al. 2002. Microarray analysis reveals a major direct role of DNA copy No. alteration in the transcriptional program of human breast tumors.PNAS, 99(20):12963-12968.
Singleton, et al. 1992. Clinical and pathologic significance of the c-erbB-2 (HER-2
eu) oncogene.Pathol. Annu., 1(27):165-190.
Zhigang, et al. 2004. Prostate stem cell antigen (PSCA) expression in human prostate cancer tissues and its potential role in prostate carcinogenesis and progression of prostate cancer.World Journal of Surgical Oncology, 2:13.
2002-2003 Catalog & Technical Reference, New England BioLabs, Inc., p. 122.
Alberts, et al. 1994.Molecular Biology of the Cell, 3rd Edition, pp. 1216-1217. New York: Garland Publishing.
Allman, et al. 1996. BCL-6 expression during B-cell activation.Blood, 87(12):5257-5268.
Anderson, et al. 1997. A comparison of selected mRNA and protein abundances in human liver.Electrophoresis, 18:533-537.
Chen, et al. 2002. Discordant protein and mRNA expression in lung adenocarcinomas.Molecular&Cellular Proteomics 1.4, pp. 304-313.
Fessler, et al. 2002. A genomic and proteomic analysis of activation of the human neutrophil by lipopolysaccharide and its mediation by p38 mitogen-activated protein kinase.The Journal of Biological Chemistry, 277(35):31291-31302.
Fu, et al. 1996. Translational regulation of human p53 gene expression.The EMBO Journal, 15(16):4392-4401.
Gökmen-Polar, et al. 2001. Elevated protein kinase C βII is an early promotive event in colon carcinogenesis.Cancer Research, 61:1375-1381.
Hanash, S. 2003. Making sense of microarray data to classify cancer.The Pharmacogenomics Journal, 3:308-311.
Hanash, S. Mar. 2005. Integrated global profiling of cancer.Nature Reviews, Applied Proteomics Collection, pp. 9-14.
Hancock, W. S. 2004. Do we have enough biomarkers?Journal of Proteome Research, 3(4):685.
Haynes, et al. 1998. Proteome analysis: Biological assay or data archive?Electrophoresis, 19:1862-1871.
Hu, et al. 2003. Analysis of genomic and proteomic data using advanced literature mining.Journal of Proteome Research, 2:405-412.
Jang, et al. 1997. An examination of the effects of hypoxia, acidosis, and glucose starvation on the expression of metastis-associated genes in murine tumor cells.Clin. Exp Metastasis, 15(5):469-483.
Konopka, et al. 1986. Variable expression of the translocatedc-abloncogene in Philadelphia-chromosome-positive B-lymphoid cell lines from chronic myelogenous leukemia patients.Proc. Natl. Acad. Sci. USA,83:4049-4052.
Labaer, Joshua. 2003. Letter to the editor: Mining the literature and large datasets.Nature Biotechnology, 21(9):976-977.
Lewin, B. 1994. Oncogenes: Gene expression and cancer, Chap. 39, pp. 1196-1201.Genes V. New York: Oxford University Press.
Lian, et al. 2001. Genomic and proteomic analysis of the myeloid differentiation program.Blood, 98(3):213-524.
Ohara, et al. 2001. Directional cDNA library construction assisted by the in vitro recombination reaction.Nucleic Acids Research, 29(4):e22 p. 1-8.
Powell, et al. 1998. Expression of cytochrome P4502E1 in human liver: Assessment by mRNA, genotype and phenotype.Pharmacogenetics, 8:411-421. (abstract).
Tokunaga, et al. 2000. Application of quantitative RT-PCR using “TaqMan” technology to evaluate the expression of CK 18 mRNA in various cell lines.J. Exp. Clin. Cancer Res., 19(3):375-381.
Vallejo, et al. 2000. Evidence of tissue-specific, post-transcriptional regulation of NRF-2 expression.Biochimie, 82(12):1129-1133. (Abstract).
Wang, et al. 1996. mRNA Differential display: Application in the discovery of novel pharmacological targets.Trends Pharmacol. Sci., 17(8):276-279.
Yousef, et al. 2003. Parallel overexpression of seven kallikrein genes in ovarian cancer.Cancer Research, 63:2223-2227.
Abe, et al. “An increased high-mobility group A2 expression level is associated with malignant phenotype in pancreatic exocrine tissue.”Br J Cancer. Dec. 1, 2003;89(11):2104. (Abstract Only).
Ando, et al. “Selective apoptosis of natural killer-cell tumours by I-asparaginase.”Br. J. Haematol. Sep. 2005;130(6):860. (Abstrac

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