Estrogen receptor-β ligands

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C514S457000, C549S289000

Reexamination Certificate

active

10399010

ABSTRACT:
A method for treating a disease associated with the estrogen receptor-β, comprising the step of administiering a therapeutically-effective amount of a compound that satifies the equation: KiαA/KiβA>25, optionally having general structure (I).

REFERENCES:
patent: 5733926 (1998-03-01), Gobach
patent: 6331562 (2001-12-01), Bhagwat et al.
patent: 6518301 (2003-02-01), Barlaam et al.
patent: 0135172 (1985-03-01), None
patent: WO 9844920 (1998-10-01), None
patent: WO 9850026 (1998-11-01), None
patent: WO 00/62765 (2000-10-01), None
patent: WO 0062765 (2000-10-01), None
Kitagawa, M et al, ‘Aryloxyacetic acid diuretics with uriosuric activity. II. Substituted [(4-oxo-4H-1-benzopyran-7-yl)oxy]acetic acids and the related compounds’ CA 116:106034 (1992).
Barlaam, B et al, ‘Estrogen receptor-Beta ligands for therapy’ CA 133:317571 (2000).
Anthony, M. et al ‘What would be the properties of an ideal serm?’ Annals of the New York Academy of Sciences, (Dec. 2001) 949, 261-278.
Zhao Bian et al, “Selective Estrogen Receptor Modulators and Coronary Heart Disease,” Trends in Cardiovascular Medicine, vol. 11 (No. 2), p. 196-202, fig. 1.
Valerie L. Baker et al, “Selective Estrogen Receptor Modulators in Reporductive Medicine and Biology,” Obstetical and Gynecological Survey, vol. 55 (No. 7), p. 21-47, fig. 1.
Y.T. Van Der Schouw et al, “Phytoestrogens and cardiovascular disease risk,” Nutr. Metab. Cardiovasc. Dis., p. 154-157, fig. 1.
Joe A. Vison et al, “Plant Flavonoids, Especially Tea Flavonols, Are Powerful Antioxidants Using an in Vitro Oxidation Model for Hearth Disease,” J. Agric. Food Chem., p. 2800-2802, fig. 1.
J.J.B. Anderson et al, “Biphasic Effects of Genistein on Bone Tissue in the Ovariectomized, Lactating Rat Model,” Society of the Society for experimental biology and medicine, p. 345-350, fig. 1.
John JB Anderson et al, “Health potential of soy isoflavones for menopausal women,” Public Health Nutration, vol. 2 (No. 4), p. 489-504, fig. 1.
Ann Vincent et al, “Soy Isofavones: Are they useful in menopause?,” Mayo Clinic Proc, p. 1174-1184, fig. 1.
J. Huber, “Phytoostrogene und SERMs, Alternativen zur klassischen Hormontherapie?,”Therapeutische Umschau, p. 651-654.

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