Method for making...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Reexamination Certificate

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11411952

ABSTRACT:
The present invention relates to methods for making racemic 2-(7-chloro -1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxohexyl)-1-isoindolinone and (+)-2-(7 -chloro-1,8-naphthyridine-2-yl)-3-(5-methyl-2-oxo-hexyl)-1-isoindolinone.

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Newkome et al., Journal of Organic Chemistry, “Chemistry of heterocyclic compounds. 61. synthesis and conformational studies of macrocycles possessing 1,8-or 1,5-Naphthyridino subunits connected by carbon-oxygen bridges”, 1981, vol. 46, pp. 833-839.

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