Inactivated mycoplasma hyopneumoniae and uses therefor

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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C424S184100, C424S203100, C424S234100, C424S254100, C424S255100, C424S253100, C424S240100, C424S825000, C424S093100, C424S093300, C435S236000, C435S235100, C435S253100, C435S243000, C435S245000, C435S237000, C435S238000

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10914024

ABSTRACT:
The invention relates to a method for making an inactivated vaccine ofMycoplasma hyopneumoniaeby inactivating the bacteria with Thimerosal. The resulting bacterin is mixed with an adjuvant of aluminum hydroxide and DEAE dextran and injected into pigs. The resulting bacterin and adjuvant mixture can also be mixed with other bacteria such as Bordetella and Pasteurella, for further adjuvant effect. Protective immunity against mycoplasmal pneumonia is elicited in swine using these vaccines.

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