Process for producing propargylcarbinol compounds

Details Process for producing propargylcarbinol compounds Process for producing propargylcarbinol compounds

1995-02-13

1996-06-04

Raymond, Richard L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Oxygen containing

568878, 568879, 568813, 568821, 568850, 549 78, 549497, C07C 2914, C07C 29143, C07C 3303

Patent

active

055234950

ABSTRACT:
The present invention provides a process for producing a propargylcarbinol compound of formula (I): ##STR1## wherein R.sup.1 and R.sup.2 are as defined herein. The process comprises reacting a haloallylcarbinol compound of formula (II) with a base. The present invention also relates to a process for producing the haloallylcarbinol compound. The above propargylcarbinol compound is useful as an intermediate for agrochemicals, pharmaceuticals, perfumes, resin monomers, and the like.

REFERENCES:
patent: 4933511 (1990-06-01), Gredley et al.
patent: 4990697 (1991-02-01), Renge et al.
patent: 5091598 (1992-02-01), Cahiez et al.
patent: 5189186 (1993-02-01), Saito et al.
patent: 5239092 (1993-08-01), Saito et al.
patent: 5254756 (1993-10-01), Banzinger et al.
Organic Reactions, vol. 5 (1949), Jacobs, "The Synthesis of Acetylenes".
Tetrahedron Letters, No. 51, pp. 4723-4724 (1976) (W/Translation) Gorgues et al., "Dehydrohalogenation to Acetylens By Ion Pair Extraction".
Chemical Abstracts, 110:192517h Preparation of Propargyl Ketones as Intermediates for Prostaglandins . . . (EP 290,905), Gerhard et al., (1988).
J. Org. Chem. 49, 172 (1984), Mandia et al., "Facile One-Pot Synthesis of Bromo Homoallyl Alcohols and 1,3-keto Acetates in Allytin Intermediates", Tetrahedron Lett. 26, 1449 (1985).
Petrier et al. (I), "Selective Tin and Zinc Mediated Allylations of Carbonyl Compounds in Aqueous Media", J. Org. Chem. 47, 2484 (1982).
Petrier et al. (II), "Allyl/zinc Additions in Aqueous Media", J. Org. Chem. 1985, 50, 910-912.
Minamii et al., "Prep. of 2-halogeno-4-hydroxy-4-methyl-1-octene as Intermediates for Prostaglandins", CA114(17):163523j.

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