Polymorphic forms of naltrexone

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S282000

Reexamination Certificate

active

10860608

ABSTRACT:
This invention relates to the discovery of novel polymorphic forms of naltrexone, including solvates, hydrates, anhydrous and other crystalline forms and combinations thereof. These novel forms of naltrexone impart advantages in pharmaceutical formulations incorporating them, including sustained release, or long acting, formulations.

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Brittain et al. “Polymorphic forms of naltrexone” CA 142:43831 (2004).
Braga et al. “Making crystals from crystals . . . ” Chem. Commun. (2005), p. 3635-3645.

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