Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1994-01-26
1996-06-04
Killos, Paul J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
A01N 4350
Patent
active
055233171
ABSTRACT:
Disclosed is a method of reducing blood pressure which comprises administering to a patient an imidazole derivative of the formula: ##STR1## wherein: each of R.sup.1 and R.sup.2 is hydrogen, substituted or unsubstituted alkyl, alkoxyalkyl, cycloalkyl, aryl, aralkyl, or R.sup.1 and R.sup.2 are combined to form hetero ring; each of R.sup.3, R.sup.4, R.sup.5 and R.sup.6 is hydrogen, halogen, substituted or unsubstituted alkoxy, substituted or unsubstituted alkyl, aryl, aryloxy, alkoxycarbonyl, nitro, amino, acyl, or R.sup.3 is combined with R.sup.2 to form heteroring; R.sup.7 is hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted aryl, substituted or unsubstituted arylcarbonyl, or S-containing heteroring; each of R.sup.8 and R.sup.9 is hydrogen, halogen, substituted or unsubstituted alkoxy, unsubstituted or substituted alkyl, alkoxycarbonyl, aralkyl, nitro, amino, acyl, substituted or unsubstituted aryl, or R.sup.8 and R.sup.9 are combined to from alkylene; and n is 0 or 1.
REFERENCES:
CA 120:69232 1993.
Hara Fumiyo
Kamishiro Toshiro
Masaki Mitsuo
Killos Paul J.
Nippon Chemiphar Co., Ltd.
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