Treatment of ADHD

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C546S277400

Reexamination Certificate

active

10477382

ABSTRACT:
The use of 3-[1-[2-(1-acetyl-2,3-dihydro-1H-indol-3-yl)ethyl]-1,2,3,6-tetrahydropyridin-4-yl]-6-chloro-1H-indole, any of its enantiomers and pharmaceutically acceptable salts thereof for the preparation of a pharmaceutical composition for the treatment of attention deficit hyperactivity disorder.

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patent: 6656953 (2003-12-01), Hoemann
patent: WO-98/28293 (1998-07-01), None
Tarazi et al. I, “Dopamine D4 receptos, etc.,” Molecular Psychiatry, 1999, 4, 529-538.
Paterson et al., “Dopamine D4 Receptor, etc.,” Neuropsychopharmacology, 1999, 21 (1) 3-16.
Todd et al., “The dopamine receptor, etc.,” Trends in Pharmacological Sciences 22 (2), 2001, 55-56.
Tarazi et al., II, “Dopamine D4 Receptors, etc.,” Journal of Receptors and Signal Transduction, 24 (3), 2004, 131-147.
J.T. McCracken, et al., “Evidence for linkage of a tandem duplication polymorphism upstream of the dopamine D4 receptor gene (DRD4) with attention deficit hyperactivity disorder (ADHD)”, Molecular Psychiatry, vol. 5, (2000), pp. 531-536.

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