Substituted-cycloalkyl and oxygenated-cycloalkyl glucokinase...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C514S336000, C514S371000, C514S459000, C514S460000, C514S471000, C544S336000, C546S282100, C548S195000, C549S419000, C549S493000, C549S494000, C549S495000, C549S496000

Reexamination Certificate

active

11402167

ABSTRACT:
2,3-Di-substituted N-heteroaromatic propionamides with said substitution at the 2-position being a substituted phenyl group and at the 3-position being a polar ring, said propionamides being glucokinase activators which increase insulin secretion in the treatment of type II diabetes.

REFERENCES:
patent: 3431301 (1969-03-01), Focella et al.
patent: 3776917 (1973-12-01), Mann et al.
patent: 5113013 (1992-05-01), Powell et al.
patent: 5169951 (1992-12-01), Sutter et al.
patent: 5556859 (1996-09-01), Johnson
patent: 249 241 (1912-07-01), None
patent: 0566138 (1993-10-01), None
patent: 1436502 (1976-05-01), None
patent: WO 00/26202 (2000-05-01), None
patent: WO 00 58293 (2000-10-01), None
patent: WO 02 08209 (2002-01-01), None
Colowick, S.P., The Enzymes, vol. 9 (P. Boyer, ed.) Academic Press, New York, NY, p. 1-48 (1973).
Chipkin, et. al., in Joslin's Diabetes (C.R. Kahn and G.C. Wier, eds.), Lea and Febiger, Philadelphia, PA, p. 97-115 (1994).
Printz, et. al., Ann. Rev. Nutrition, vol. 13 (R.E. Olson, D.M. Bier, and D.B. McCormick, eds.) Annual Review Inc, Palo Alto, CA pp. 463-496 (1993).
Meglasson, et al., Amer. J. Physiol., 246, E1-E13 (1984).
Grupe, et al., Cell 83, 69-78, (1995).
Ferre, et al., FASEB J., 10, 1213-1218 (1996).
Liang, et al., Biochem. J. 309, 167-173 (1995).
Glaser, et al. New England J. Med. 338, 226-230 (1998).
Rodier, et. al., Acta Crystallogr., C46 (1990) pp. 154-156.
Robert, J. M. H., et. al., Eur J. Med. Chem. vol. 29, (1994), pp. 841-854.
Spickett, et. al., Eur. J. Med. Chem.-Chimica Therapeutica, vol. 11(1), (1976), pp. 7-12.
Bhat, A. R., et. al., J. Inst. Chemists (India), vol. 61, 1989, pp. 134-136.
Spielman, M.A., et. al., J. Am. Chem. Soc., 70 (1948), pp. 4189-4191.

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