Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1980-10-17
1982-03-30
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
546106, C07D21910, A61K 3147
Patent
active
043224245
ABSTRACT:
The invention concerns a crystalline monogluconate salt of the antitumor agent 4'-(9-acridinylamino)-methanesulfon-m-anisidide and compositions comprising mixtures of such salt with an organic acid selected from gluconic acid, gluconolactone or mixtures thereof. The novel salt and compositions are characterized in having unexpectedly high water-solubility.
REFERENCES:
patent: 3839344 (1974-10-01), Sherlock
patent: 4258191 (1981-03-01), Dubicki et al.
Cain et al., European Journal of Chemistry, vol. 10, pp. 539-549, Pub. in Great Britain, (1974).
The Condensed Chemical Dictionary, Ninth Edition, Pub. Van Nostrand Reinhold Company, pp. 414-415, 1977.
Lachman et al., The Theory and Practice of Industrial Pharmacy, Second Edition, pp. 521-524, (1976).
Bouzard Daniel
Granatek Edmund S.
Perol Claude
Stemer Jacques
Weber Abraham
Bristol-Myers Company
Morse David M.
Rotman Alan L.
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