Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-11-13
2007-11-13
Wilson, James O. (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S212020, C540S453000, C540S502000, C544S231000
Reexamination Certificate
active
11423557
ABSTRACT:
The invention relates to a dihydrospiro-[cycloalkylamine]-pyrimidone derivative represented by formula (I) or a salt thereof:wherein X, Y, R1, R2, R3, R4, o, m, n, p and q are as defined herein. The invention relates also to a medicament comprising the said derivative or a salt thereof as an active ingredient which is used for preventive and/or therapeutic treatment of a neurodegenerative disease caused by abnormal activity of GSK3β, such as Alzheimer disease.
REFERENCES:
patent: 2005/0267132 (2005-12-01), Banville et al.
patent: WO 02/18386 (2002-03-01), None
patent: WO 03/027115 (2003-04-01), None
patent: WO 03/027116 (2003-04-01), None
Chereze Nathalie
Lochead Alistair
Saady Mourad
Slowinski Franck
Yaiche Philippe
Gupta Balaram
Jaisle Cecilia M
Mitsubishi Pharma Corporation
Sanofi-Aventis
Wilson James O.
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