Pyrido[2,3-d]pyrimidin-7-carboxylic acid derivatives, their...

Details Pyrido[2,3-d]pyrimidin-7-carboxylic acid derivatives, their... Pyrido[2,3-d]pyrimidin-7-carboxylic acid derivatives, their...

2007-01-16

2007-01-16

Rao, Deepak (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S252160, C514S264110, C544S122000, C544S279000

Reexamination Certificate

active

10809067

ABSTRACT:
The invention describes compounds of the general formula Ia process for their manufacture, medicaments containing them and their manufacture as well as the use of these compounds as pharmaceutically active agents. The compounds show activity as protein kinase inhibitors, in particular src family tyrosine kinase inhibitors, and may therefore be useful for the treatment of diseases mediated by said tyrosine kinases.

REFERENCES:
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patent: WO 02/080360 (2002-10-01), None
patent: WO 02/090360 (2002-11-01), None
patent: WO 03/000011 (2003-01-01), None
Simone, Oncology: Introduction, Cecil Textbook of Medicine, 20thEdition, vol. 1, pp. 1004-1010, 1996.
Traxler, Protein Tyrosine Kinase Inhibitors in Cancer Treatment, Exp. Opin. Ther. Patents, 7(6):571-588, 1997.

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