High throughput screen for inhibitors of the folate...

Details High throughput screen for inhibitors of the folate... High throughput screen for inhibitors of the folate...

2007-04-10

2007-04-10

Vogel, Nancy (Department: 1636)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

Reexamination Certificate

active

09925824

ABSTRACT:
Methods for identifying compounds that are inhibitors of bacterial tetrahydrofolate biosynthesis are disclosed. Such compounds can be used as lead compounds in methods for preparing antibacterial agents for treating bacterial infections (e.g., in humans, animals, and plants). The disclosed methods allow for high throughput screening of libraries of test compounds.

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