Colloidal suspension of submicronic particles for carrying...

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S002600, C516S077000

Reexamination Certificate

active

10398134

ABSTRACT:
A suspension of biocompatible particles based on a double-block hydrophilic neutral polyminoacid/hydrophobic neutral polyaminoacid copolymer and suitable for carrying active principles. The carrier particles can combine in colloidal suspension in a non-dissolved state with an active principle and release same, particularly in vivo, in prolonged and/or delayed delivery. The carrier particles may be derived from a powdery solid, and spontaneously form stable aqueous suspensions in the absence of surfactants or organic solvents. The invention also concerns the carrier particles in dry form, the method of preparing them, and pharmaceutical compositions (in dry form or suspension) which include the carrier particles associated with an active principle.

REFERENCES:
patent: 4351337 (1982-09-01), Sidman
patent: 4450150 (1984-05-01), Sidman
patent: 5286495 (1994-02-01), Batich et al.
patent: 5449513 (1995-09-01), Yokoyama et al.
patent: 5510103 (1996-04-01), Yokoyama et al.
patent: 5780579 (1998-07-01), Soula et al.
patent: 5904936 (1999-05-01), Huille et al.
patent: 6180141 (2001-01-01), Lemercier et al.
patent: 6630171 (2003-10-01), Huille et al.
patent: 2001/0000510 (2001-04-01), Sakurai et al.
patent: 0 583 955 (1994-02-01), None
patent: 0 721 776 (1996-07-01), None
patent: WO88/01213 (1988-02-01), None
patent: WO89/08449 (1989-09-01), None
patent: WO91/06286 (1991-05-01), None
patent: WO91/06287 (1991-05-01), None
patent: WO96/29991 (1996-10-01), None
patent: WO97/02810 (1997-01-01), None
patent: WO 01/37809 (2001-05-01), None
Constancies A., (Journal of Colloid & Interface Science 217, 357-368, 1999).
Chou, Peter Y. (Biochemistry 11(16), 3028-43, 1972).
Akiyoshi, Chemistry Letters, vol. N8, 707-708, 1995.
Candau, S., Chapter 3 of Light Scattering in Surfactant solutions, vol. 22, Ed. R. Zana, M. Dekker, Inc., New York (1984) pp. 147-207).
Hayashi, Toshio (Polymer Journal (Tokyo, Japan) 17(12), 1273-80, 1985).
Wojcik, J. (Macromolecules 23(15), 3655-62, 1990).
Harada et al., “Formation of Polyion Complex Micelles in an Aqueous Milieu From a Pair of Oppositely-Charged Block Copolymers With Poly(ethylene Glycol)Segments,” 28Macromolecules28 5294 (1995).
W.D. Fuller,A procedure for the facile synthesis of amino-acid N-carboxyanhydrides, Biopolymers (1976) vol. 15, pp. 1869-1871.
Harada et al.,Formation of Polyion Complex Micelles in an Aquous Milieu from a Pair of Oppositely-Charged Block Copolymers with Poly(Ethylene Glycol) Segments, Macromolecules, (1995) vol. 28, pp. 5294-5299.
M.J. Humphrey,Delivery System for Peptide Drugs, eds. S. Davis et al., Plenum Press, N.Y. (1986), pp. 139-151.
F. Touraud et al., copending U.S. Appl. No. 10/130,783, filed Aug. 5, 2002 as the National Stage of International Application No. PCT/FR00/02831.
Tsutsumiuchi et al.,Synthesis of Polyoxazoline—(Glyco)peptide Block Copolymer Ring-Opening Polymerization of(Sugar-Substituted) αAmino Acid N-Carboxyanhydrides with Polyoxazoline Macroinitiators, Macromolecules (1997) vol. 30, pp. 4013-4017.
Akiyoshi et al. “Stabilization of insulin upon supramolecular complexation with hydrophobized polysaccharide nanoparticle” Chemistry letters N8: 707-708 (1995).
S. Candau, “Chapter 3, Light Scattering, In Surfactant Solutions” vol. 22 Ed. R. Zaria, M. Dekker, Inc. New York pp. 147-202 (1994).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Colloidal suspension of submicronic particles for carrying... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Colloidal suspension of submicronic particles for carrying..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Colloidal suspension of submicronic particles for carrying... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3799389

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.